2.7.1.5: rhamnulokinase

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For detailed information about rhamnulokinase, go to the full flat file.

Reaction

Synonyms

kinase, rhamnulo-(phosphorylating), L-rhamnulokinase, L-rhamnulose kinase, RhaB, rhamnulose kinase, RhuK

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.5 rhamnulokinase

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Results	in table
3613	AA Sequence
1	Application
1	CAS Registry Number
2	Cloned(Commentary)
1	Cofactor
2	Crystallization (Commentary)
8	KM Value [mM]
4	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
184	Organism
7	Pathway
5	PDB ID
1	pH Optimum
1	Purification (Commentary)
1	Reaction
1	Reaction Type
9	Reference
1	Specific Activity [micromol/min/mg]
19	Substrates and Products (Substrate)
2	Subunits
10	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

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Application on EC 2.7.1.5 - rhamnulokinase

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APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

synthesis

Thermotoga maritima MSB8

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production of L-Rhamnulose (6-deoxy-L-arabino-2-hexulose) and L-fuculose (6-deoxy-L-lyxo-2-hexulose) from L-rhamnose and L-fucose. First, isomerization of L-rhamnose to L-rhamnulose, or L-fucose to L-fuculose is combined with a targeted phosphorylation reaction catalyzed by L-rhamnulose kinase (RhaB). The by-products (ATP and ADP) are selectively removed by silver nitrate precipitation method. In the second step, the phosphate group is hydrolyzed to produce L-rhamnulose or L-fuculose with purity exceeding 99% in more than 80% yield

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