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2.7.1.40: pyruvate kinase

This is an abbreviated version!
For detailed information about pyruvate kinase, go to the full flat file.

Word Map on EC 2.7.1.40

Reaction

ATP
+
pyruvate
=
ADP
 +
phosphoenolpyruvate

Synonyms

ATP/pyruvate O'-phosphotransferase, ATP:pyruvate 2-O-phosphotransferase, CPK, CPK1, cPK2, cPK3, cPK4, cPK5, CTHBP, cytosolic pyruvate kinase, cytosolic thyroid hormone binding protein, EHI_098420, EhPK, EhPyk, erythroid (R-type) pyruvate kinase, fluorokinase, hL-PYK, hLPYK, hPKM2, K+-dependent PK, K+-independent PK, kinase, fluoro- (phosphorylating), kinase, pyruvate (phosphorylating), L-PK , L-PYK, liver PK, liver pyruvate kinase, M1-PK, M1-PYK, M2 pyruvate kinase, M2 type phosphoenolpyruvate kinase, M2-PK, M2-pyruvate kinase, M2-type pyruvate kinase, M2PK, mPKM2, MRSA PK, muscle PK, NCgl2008, NCgl2809, PAE0819, PfPYK, pfPyrK, phosphoenol transphosphorylase, phosphoenolpyruvate kinase, phosphoenolpyruvate: ADP phosphotransferase, PK-alphabeta1, PK-alphabeta2, PK-M1, PK-M2, PK-R, PK-S, PK1, PK3, PKC, PKC1, PKL, Pklr, PKM1, PKM2, PKp, ProTalphaK, PYK, PYK-I, Pyk1, Pyk2, PykA, PykF, PyKII, pyruvate kinase, pyruvate kinase 1, pyruvate kinase isoenzyme M2, pyruvate kinase isoform M2, pyruvate kinase isoforms 2, pyruvate kinase isozyme M1, pyruvate kinase isozyme type M2, pyruvate kinase M1, pyruvate kinase M2, pyruvate kinase M2 isoform, pyruvate kinase muscle isoform 2, pyruvate kinase muscle isozyme, pyruvate kinase type M2, pyruvate kinase type-II, pyruvate phosphotransferase, pyruvic kinase, R-type pyruvate kinase, R-type/L-type pyruvate kinase, red cell/liver pyruvate kinase, rM1-PYK, RMPK, RPK, Rv1617, SSO0981, TbrPYK, TCIL3000_10_12020, TcoPYK, THBP1, TuM2-PK, tumor cell specific pyruvate kinase isozyme M2, tumour M2-PK, tumour M2-pyruvate kinase, VcIIPK, VcIPK, VC_0485, VC_2008, VEG17, vegetative protein 17, vesicle-associated pyruvate kinase, YPK

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.40 pyruvate kinase

Molecular Weight

Molecular Weight on EC 2.7.1.40 - pyruvate kinase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100000
115000
-
gel filtration
120000 - 170000
analytical ultracentrifugation
152000
Pigeon
-
gel filtration
180000 - 190000
-
gel filtration
190000
194000
-
native enzyme, gel filtration
195000 - 205000
-
gel filtration
200000
2000000
-
PK I
203000
205000
-
gel filtration
207000
-
gel filtration
209400
-
sedimentation equilibrium method
210000
214000
-
gel filtration
215000
216000
-
isozyme PK1, PAGE
220000
220000 - 240000
gel filtration
224000
225000 - 240000
-
isozyme PK I
225500
227000
-
average MW of all 5 isoforms, PAGE
230000
230700
-
gel filtration
232000
-
gel filtration
232600
Busycotypus canaliculatum
-
PK-anoxic, gel filtration
234000
-
gel filtration
235000
237000
-
sucrose density gradient centrifugation
237500
Busycotypus canaliculatum
-
PK-aerobic, gel filtration
238000
239000
-
isozyme PK5, PAGE
240000
242000
-
sedimentation analysis
250000
265000
-
liver, gel filtration
270000
280000
-
gel filtration
282000
-
gel filtration
286000
Busycotypus canaliculatum
-
PK-aerobic, gel filtration
299800
Busycotypus canaliculatum
-
PK-anoxic, gel filtration
300000
305000
-
gel filtration
380000
-
gel filtration
400000
-
growing and resting cells, FPLC gel filtration
44000
-
4 * 44000, SDS-PAGE
463000
-
gel filtration
47000
-
4 * 47000, isozyme II, SDS-PAGE
476000
-
gel filtration
48000
-
4 * 48000, SDS-PAGE
49000
49680
-
4 * 49680
49800
x * 50000, SDS-PAGE, x * 49800, calculated
50000
50500
-
4 * 50500, PykF, SDS-PAGE, circular dichroism spectroscopy, and gel filtration, 4 * 51500, PykA, SDS-PAGE, circular dichroism spectroscopy, and gel filtration
51000
51300
4 * 51300, SDS-PAGE
51400
-
calculated from amino acid sequence
51500
-
4 * 50500, PykF, SDS-PAGE, circular dichroism spectroscopy, and gel filtration, 4 * 51500, PykA, SDS-PAGE, circular dichroism spectroscopy, and gel filtration
52000
-
4 * 52000, L-type isozyme
53100
4 * 65100, about, full-length enzyme, sequence calculation, 4 * 53100, about, C-terminally truncated enzyme mutant, sequence calculation
53500
-
x * 53500, SDS-PAGE
54000
54400
55000
55400
2 * 55400, SDS-PAGE, predominantly a dimer, but also some tetramer
56000
57590
calculated from amino acid sequence
57800
-
gel filtration
57900
58000
580000
-
resting cells, FPLC gel filtration
58600
-
4 * 58600, M4-type isozyme, SDS-PAGE
59000
590000
-
isozyme PK1
59500
-
4 * 59500, K4-type isozyme, SDS-PAGE
60000
61940
x * 61940, deduced from gene sequence
62000
62200
-
calculated from amino acid sequence
62570
x * 62570, deduced from gene sequence
63000
-
4 * 63000, SDS-PAGE
64400
Busycotypus canaliculatum
-
4 * 64400, PK-aerobic, SDS-PAGE
64500
-
SDS-PAGE, subunit
65000
-
4 * 65000, SDS-PAGE
65100
4 * 65100, about, full-length enzyme, sequence calculation, 4 * 53100, about, C-terminally truncated enzyme mutant, sequence calculation
66000
69900
-
4 * 69900
70000
71000
Busycotypus canaliculatum
-
4 * 71000, PK-aerobic, SDS-PAGE
72600
Busycotypus canaliculatum
-
4 * 72600, PK-anoxic, SDS-PAGE
73000
-
4 * 73000, SDS-PAGE
77000
-
purified recombinant protein
80000
additional information