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2.7.1.35: pyridoxal kinase

This is an abbreviated version!
For detailed information about pyridoxal kinase, go to the full flat file.

Word Map on EC 2.7.1.35

Reaction

ATP
+
pyridoxal
=
ADP
 +
pyridoxal 5'-phosphate

Synonyms

ePL kinase, ePL kinase 1, hPL kinase, HPLK, kinase (phosphorylating), pyridoxal, kinase, pyridoxal (phosphorylating), LdPdxK, PdxK, pdxY, PKH, PL kinase, PLK, Plk1, PM kinase, PN kinase, PN/PL/PM kinase, pyridoxal 5-phosphate-kinase, pyridoxal kinase, pyridoxal kinase 1, pyridoxal kinase PKL, pyridoxal kinase-like protein SOS4, pyridoxal phosphokinase, pyridoxal/pyridoxine kinase, pyridoxamine kinase, pyridoxine kinase, pyridoxine/pyridoxal/pyridoxamine kinase, salt overly sensitive4, SAV0580, Sos4, StPLK, vitamin B6 kinase

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.35 pyridoxal kinase

Specific Activity

Specific Activity on EC 2.7.1.35 - pyridoxal kinase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.004
-
brain enzyme
0.0125
0.02
-
substrate: methyl N-[[3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl]methyl]tryptophanate
0.038
-
substrate: methyl (1S)-1-[3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl]-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylate
0.052
-
purified kinase 2 enzyme, pH 6.1, 37°C
0.064
-
substrate: methyl N-[[3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl]methyl]histidinate
0.07
crude enzyme, in 70 mM potassium phosphate (pH 5.5), 0.5 mM ZnCl2, at 37°C
0.0713
-
-
0.112
0.1447
-
-
1.27
-
reaction with pyridoxal
1.42
-
reaction with pyridoxine
1.8
crude enzyme, in 70 mM potassium phosphate (pH 5.5), 0.5 mM ZnCl2, at 37°C
1847
purified recombinant His-tagged wild-type enzyme, pH 7.2, 37°C
2.105
-
-
2.47
-
-
2.5
purified enzyme, pH 6.1, 37°C
2.7
-
purified kinase 1 enzyme, pH 6.1, 37°C
additional information