2.7.1.33: pantothenate kinase
This is an abbreviated version!
For detailed information about pantothenate kinase, go to the full flat file.
Word Map on EC 2.7.1.33
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2.7.1.33
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neurodegeneration
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kinase-associated
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panks
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sign
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dystonia
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ganglia
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hallervorden-spatz
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extrapyramidal
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parkinsonism
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eye-of-the-tiger
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pla2g6
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phosphopantothenate
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dysarthria
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tiger
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neuroaxonal
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phosphopantetheine
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hypointensity
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medicine
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4'-phosphopantothenate
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pigmentary
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pantothenamide
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bradykinesia
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synthesis
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atp13a2
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4'-phosphopantetheine
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pantethine
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drug development
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neuroferritinopathy
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choreoathetosis
-
phosphopantothenoylcysteine
- 2.7.1.33
- neurodegeneration
-
kinase-associated
-
panks
- sign
- dystonia
- ganglia
- hallervorden-spatz
-
extrapyramidal
- parkinsonism
-
eye-of-the-tiger
- pla2g6
- phosphopantothenate
- dysarthria
- tiger
-
neuroaxonal
- phosphopantetheine
-
hypointensity
- medicine
- 4'-phosphopantothenate
-
pigmentary
- pantothenamide
-
bradykinesia
- synthesis
-
atp13a2
- 4'-phosphopantetheine
- pantethine
- drug development
-
neuroferritinopathy
-
choreoathetosis
-
phosphopantothenoylcysteine
Reaction
Synonyms
4-phosphopantoate, BaPanK, Cab1, Cab1p, CoaA, coaW, CoaX, D-pantothenate kinase, EhPAnK, fumble, hPanK, hPanK1, hPANK2, hPanK3, hPanK4, HpPanK-III, HsPANK3, HsPANK4, kinase, pantothenate (phosphorylating), More, mPank, mPank1, mPanK2, mPanK3, MtCoaA, MtPanK, PAK, PanK, PanK-III, PanK1, PanK1alpha, PanK1b, PanK2, PanK3, PanK4, PanKBa, pantothenate kinase, pantothenate kinase 1, pantothenate kinase 2, pantothenate kinase 3, pantothenate kinase 4, pantothenate kinase-2, pantothenic acid kinase, PfPanK, Pfpank1, PoK, rPanK4, Rts protein
ECTree
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KCat KM Value
KCat KM Value on EC 2.7.1.33 - pantothenate kinase
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0.5
(2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-[[(piperidin-4-yl)methyl]amino]propyl)butanamide
at pH 7.6, temperature not specified in the publication
0.3
(2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-[[2-(piperazin-1-yl)ethyl]amino]propyl)butanamide
at pH 7.6, temperature not specified in the publication
11
(2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-[[2-(pyridin-2-yl)ethyl]amino]propyl)butanamide
at pH 7.6, temperature not specified in the publication
0.1
(2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-[[2-oxo-2-(pentylamino)ethyl]amino]propyl)butanamide
at pH 7.6, temperature not specified in the publication
2.9
(2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-[[3-(morpholin-4-yl)propyl]amino]-3-oxopropyl)butanamide
at pH 7.6, temperature not specified in the publication
5.1
(2R)-2,4-dihydroxy-3,3-dimethyl-N-[(1-pentyl-1H-1,2,3-triazol-4-yl)methyl]butanamide
at pH 7.6, temperature not specified in the publication
0.5
(2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-(1-propyl-1H-1,2,3-triazol-4-yl)propyl]butanamide
at pH 7.6, temperature not specified in the publication
26
(2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(pentylamino)propyl]butanamide
at pH 7.6, temperature not specified in the publication
24
(2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(phenylamino)propyl]butanamide
at pH 7.6, temperature not specified in the publication
3.2
(2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(pyrimidin-4-ylamino)propyl]butanamide
at pH 7.6, temperature not specified in the publication
35
(2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(3-phenylpropyl)amino]propyl]butanamide
at pH 7.6, temperature not specified in the publication
20
(2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(pyridin-2-ylmethyl)amino]propyl]butanamide
at pH 7.6, temperature not specified in the publication
38
(2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(pyridin-3-ylmethyl)amino]propyl]butanamide
at pH 7.6, temperature not specified in the publication
7
(2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(pyridin-4-ylmethyl)amino]propyl]butanamide
at pH 7.6, temperature not specified in the publication
20
(2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-[(3-methylpyridin-2-yl)amino]-3-oxopropyl]butanamide
at pH 7.6, temperature not specified in the publication
21
(2R)-2,4-dihydroxy-N-(3-[[3-(1H-imidazol-1-yl)propyl]amino]-3-oxopropyl)-3,3-dimethylbutanamide
at pH 7.6, temperature not specified in the publication
1.9
(2R)-N-[3-(1,3-dihydro-2H-isoindol-2-yl)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide
at pH 7.6, temperature not specified in the publication
0.4
(2R)-N-[3-(2,3-dihydro-1H-indol-1-yl)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide
at pH 7.6, temperature not specified in the publication
17
(2R)-N-[3-(benzylamino)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide
at pH 7.6, temperature not specified in the publication
4.5
(2R)-N-[3-[(2-butanamidoethyl)amino]-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide
at pH 7.6, temperature not specified in the publication
5.1
(2S)-2-hydroxy-3-(hydroxymethyl)-3-methyl-N-[3-oxo-3-(pentylamino)propyl]pentanamide
at pH 7.6, temperature not specified in the publication
9
(2S)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-N-[3-oxo-3-(pentylamino)propyl]hept-6-ynamide
at pH 7.6, temperature not specified in the publication
0.2 - 1.5
(2S)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-N-[3-oxo-3-(pentylamino)propyl]hex-5-enamide
50
(R)-pantothenate
at pH 7.6, temperature not specified in the publication
0.3
3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]-2-(pentylamino)propanoate
at pH 7.6, temperature not specified in the publication
0.095
GTP
-
in citrate buffer, pH 6.5, temperature not specified in the publication
10
N-[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]-beta-alanyl-N-pentylglycinamide
at pH 7.6, temperature not specified in the publication
17
pantheteine
at pH 7.6, temperature not specified in the publication
0.2
at pH 7.6, temperature not specified in the publication
1.5
(2S)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-N-[3-oxo-3-(pentylamino)propyl]hex-5-enamide
at pH 7.6, temperature not specified in the publication
0.084
ATP
-
in citrate buffer, pH 6.5, temperature not specified in the publication