2.7.1.30: glycerol kinase
This is an abbreviated version!
For detailed information about glycerol kinase, go to the full flat file.
Word Map on EC 2.7.1.30
-
2.7.1.30
-
glycerol-3-phosphate
-
triglyceride
-
adrenal
-
hypoplasia
-
dystrophy
-
muscular
-
adipose
-
3-phosphate
-
duchenne
-
lipase
-
phosphoenolpyruvate
-
hexokinase
-
x-linked
-
dihydroxyacetone
-
contiguous
-
adipocytes
-
triacylglycerols
-
carboxykinase
-
congenita
-
gluconeogenesis
-
glycerophosphate
-
lipolysis
-
hpr
-
iiaglc
-
1,6-bisphosphate
-
hypogonadism
-
co-immobilized
-
phosphocarrier
-
glyceroneogenesis
-
hypogonadotropic
-
glycosomes
-
dissimilation
-
triolein
-
1,3-propanediol
-
glucose-specific
-
aquaglyceroporins
-
d-glyceraldehyde
-
phosphoenolpyruvate:sugar
-
dhap
-
phosphoenolpyruvate-dependent
-
sn-glycerol-3-phosphate
-
sn-glycerol
-
drug development
-
diagnostics
-
synthesis
- 2.7.1.30
- glycerol-3-phosphate
- triglyceride
- adrenal
- hypoplasia
- dystrophy
- muscular
- adipose
- 3-phosphate
-
duchenne
- lipase
- phosphoenolpyruvate
- hexokinase
-
x-linked
- dihydroxyacetone
-
contiguous
- adipocytes
- triacylglycerols
-
carboxykinase
- congenita
-
gluconeogenesis
- glycerophosphate
-
lipolysis
- hpr
- iiaglc
- 1,6-bisphosphate
- hypogonadism
-
co-immobilized
-
phosphocarrier
-
glyceroneogenesis
-
hypogonadotropic
- glycosomes
-
dissimilation
- triolein
- 1,3-propanediol
-
glucose-specific
-
aquaglyceroporins
- d-glyceraldehyde
-
phosphoenolpyruvate:sugar
- dhap
-
phosphoenolpyruvate-dependent
- sn-glycerol-3-phosphate
- sn-glycerol
- drug development
- diagnostics
- synthesis
Reaction
Synonyms
AFUB_068560, ASTP
ECTree
2.7.1.30 glycerol kinaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 2.7.1.30 - glycerol kinase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
ATP + D-glyceraldehyde
ADP + D-glyceraldehyde 3-phosphate
-
-
-
-
?
ADP + sn-glycerol 3-phosphate
ATP + glycerol
-
-
-
r
ADP + sn-glycerol 3-phosphate
ATP + glycerol
-
-
-
r
ATP + dihydroxyacetone
ADP + dihydroxyacetone phosphate
Candida mycoderma
-
-
-
-
?
ATP + dihydroxyacetone
ADP + dihydroxyacetone phosphate
-
-
-
-
?
ATP + dihydroxyacetone
ADP + dihydroxyacetone phosphate
-
-
-
-
?
ATP + glycerol
?
-
enzyme functions primarily in the utilization of glycerol as a carbon and energy source
-
-
?
ATP + glycerol
?
-
higher organisms: salvage of glycerol released upon lipolysis
-
-
?
ATP + glycerol
?
-
key enzyme for glycerol use in phospholipid synthesis
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
Candida mycoderma
-
-
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
Candida mycoderma
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
only glycerol active as phosphoryl group acceptor
-
-
ir
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
key enzyme of glycerol metabolism in bacteria, phosphorylation of glycerol prevents diffusion through membrane
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
-
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
high specificity for ATP, no other ribonucleoside triphosphate utilized
-
-
ir
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
high specificity for ATP, no other ribonucleoside triphosphate utilized
i.e. L-alpha-glycerophosphate
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
key enzyme of glycerol metabolism in bacteria, phosphorylation of glycerol prevents diffusion through membrane
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
-
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
enzyme deficiency causes hyperglycerolemia and glyceroluria
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme deficiency causes hyperglycerolemia and glyceroluria, provides glycerol 3-phosphate which is an important intermediate between glucose and lipid metabolism
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
involved in fat and carbohydrate metabolism, glycerol 3-phosphate is important for the synthesis of glycerides, glycerol lipids and dihydroxyacetone phosphate
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
involved in fat and carbohydrate metabolism, glycerol 3-phosphate is important for the synthesis of glycerides, glycerol lipids and dihydroxyacetone phosphate
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
Mycobacterium butyricum
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
-
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
weak: GTP, CTP, UTP, ITP
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
trout
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
CTP or UTP are as effective as ATP, not: GTP
-
-
r
ATP + glycerol
ADP + sn-glycerol 3-phosphate
-
enzyme can utilize only ATP as phosphoryl group donor
-
-
?
ATP + L-glyceraldehyde
ADP + L-glyceraldehyde 3-phosphate
Candida mycoderma
-
-
-
-
?
ATP + L-glyceraldehyde
ADP + L-glyceraldehyde 3-phosphate
-
-
-
-
?
ATP + L-glyceraldehyde
ADP + L-glyceraldehyde 3-phosphate
-
-
-
-
?
ATP + mercaptopropanediol
1-mercaptopropanediol 1-phosphate + ADP
Candida mycoderma
-
-
-
?
ATP + mercaptopropanediol
1-mercaptopropanediol 1-phosphate + ADP
Candida mycoderma
-
-
-
-
?
CTP + glycerol
CDP + glycerol 3-phosphate
-
14% of the activity with ATP
-
-
?
UTP + glycerol
UDP + glycerol 3-phosphate
-
7% of the activity with ATP
-
-
?
additional information
?
-
Candida mycoderma
-
D-glyceraldehyde promotes conversion of ATP to ADP + phosphate
-
-
?
additional information
?
-
Candida mycoderma
-
overview: enzyme catalyzes the phosphorylation of 28 nitrogen-, sulfur- and alkyl-substituted analogues of glycerol, phosphorylated products have stereochemistry analogous to that of sn-glycerol 3-phosphate
-
-
?
additional information
?
-
-
combined assay of lipase, glycerol kinase, and glycerol-3-phosphate oxidase immobilized onto nanoparticles aggregates as part of a biosensot electrode (onto nanocomposite of ZnONPs/chitosan electrodeposited onto Pt electrode)
-
-
-
additional information
?
-
-
the enzyme exhibits two-step kinetics as a function of ATP at a fixed Mg2+ concentration due to the formation of multiple Mg-ATP complexes at different Mg2+ to ATP molar ratio. The interaction of Mg2+ and ATP generates Mg-ATP complexes of various physical and chemical features in which the product composition depends on Mg2+ to ATP molar ratio among other factors such as pH, temperature, availability of other polyvalent chelating anions, as well as cations and their concentration. The Ca2+ salt of ATP is not an appropriate substrate for glycerol kinase
-
-
-
additional information
?
-
-
D-glyceraldehyde promotes conversion of ATP to ADP + phosphate
-
-
?
additional information
?
-
-
overview: enzyme catalyzes the phosphorylation of 28 nitrogen-, sulfur- and alkyl-substituted analogues of glycerol, phosphorylated products have stereochemistry analogous to that of sn-glycerol 3-phosphate
-
-
?
additional information
?
-
-
phosphate rather than D-glyceraldehyde 3-phosphate is formed, the hydrated form of this triose is phosphorylated in position 1 to yield an unstable intermediate that decomposes to D-glyceraldehyde + phosphate
-
-
?
additional information
?
-
-
overview: enzyme catalyzes the phosphorylation of 28 nitrogen-, sulfur- and alkyl-substituted analogues of glycerol, phosphorylated products have stereochemistry analogous to that of sn-glycerol 3-phosphate
-
-
?
additional information
?
-
-
overview: enzyme catalyzes the phosphorylation of 28 nitrogen-, sulfur- and alkyl-substituted analogues of glycerol, phosphorylated products have stereochemistry analogous to that of sn-glycerol 3-phosphate
-
-
?
additional information
?
-
hexameric glycerol kinase (GK) from the hyperthermophilic archaeon Thermococcus kodakarensis KOD1 (Tk-GK) is identified as the substrate-binding form of the enzyme
-
-
-
additional information
?
-
-
hexameric glycerol kinase (GK) from the hyperthermophilic archaeon Thermococcus kodakarensis KOD1 (Tk-GK) is identified as the substrate-binding form of the enzyme
-
-
-
additional information
?
-
hexameric glycerol kinase (GK) from the hyperthermophilic archaeon Thermococcus kodakarensis KOD1 (Tk-GK) is identified as the substrate-binding form of the enzyme
-
-
-
additional information
?
-
hexameric glycerol kinase (GK) from the hyperthermophilic archaeon Thermococcus kodakarensis KOD1 (Tk-GK) is identified as the substrate-binding form of the enzyme
-
-
-
additional information
?
-
in addition to its widely known and expected phosphotransferase (class II) activity, TbgGK can efficiently facilitate the hydrolytic cleavage of phosphoric anhydride bonds (a class III property). 4-Nitrophenylphosphate (pNPP) dephosphorylation is TbgGK-mediated, LC-MS analysis of the TbgGK-catalyzed dephosphorylation of its physiological substrate
-
-
-
additional information
?
-
-
in addition to its widely known and expected phosphotransferase (class II) activity, TbgGK can efficiently facilitate the hydrolytic cleavage of phosphoric anhydride bonds (a class III property). 4-Nitrophenylphosphate (pNPP) dephosphorylation is TbgGK-mediated, LC-MS analysis of the TbgGK-catalyzed dephosphorylation of its physiological substrate
-
-
-
additional information
?
-
in addition to its widely known and expected phosphotransferase (class II) activity, TbgGK can efficiently facilitate the hydrolytic cleavage of phosphoric anhydride bonds (a class III property). 4-Nitrophenylphosphate (pNPP) dephosphorylation is TbgGK-mediated, LC-MS analysis of the TbgGK-catalyzed dephosphorylation of its physiological substrate
-
-
-
