2.7.1.24: dephospho-CoA kinase
This is an abbreviated version!
For detailed information about dephospho-CoA kinase, go to the full flat file.
Word Map on EC 2.7.1.24
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2.7.1.24
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adenylyltransferase
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phosphopantetheine
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pantothen
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4'-phosphopantetheine
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codhs
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copan
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analysis
- 2.7.1.24
- adenylyltransferase
- phosphopantetheine
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pantothen
- 4'-phosphopantetheine
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codhs
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copan
- analysis
Reaction
Synonyms
3'-dephospho-CoA kinase, CoaE, coenzyme A synthase, cytosolic monofunctional DPCK, dephospho coenzyme A kinase, dephospho-CoA kinase, dephospho-coenzyme A kinase, dephosphocoenzyme A, dephosphocoenzyme A kinase, dephosphocoenzyme A kinase (phosphorylating), DPCK, Dpck1, Dpck2, EhDPCK1, EhDPCK2, GTP-dependent dephospho-CoA kinase, GTP-dependent DPCK, kinase, dephosphocoenzyme A (phosphorylating), More, TK1697
ECTree
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Substrates Products
Substrates Products on EC 2.7.1.24 - dephospho-CoA kinase
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REACTION DIAGRAM
ATP + 3'-dephospho-CoA
ADP + CoA
low activity
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?
ATP + 3'-dephospho-CoA
ADP + CoA
low activity
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?
ATP + dephospho-CoA
ADP + CoA
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last step of coenzyme A biosynthesis: phosphorylation of the 3'-OH group of the ribose sugar moiety
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?
ATP + dephospho-CoA
ADP + CoA
last step of coenzyme A biosynthesis: phosphorylation of the 3'-OH group of the ribose sugar moiety
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?
ATP + dephospho-CoA
ADP + CoA
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no substrates are 3'-dephospho-alpha-carboxy-CoA
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?
ATP + dephospho-CoA
ADP + CoA
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involved in coenzyme A biosynthesis, last irreversible reaction
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?
ATP + dephospho-CoA
ADP + CoA
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final step of coenzyme A biosynhesis
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?
ATP + dephospho-CoA
ADP + CoA
Thermus thermophilus HB8 / ATCC 27634 / DSM 579
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final step of coenzyme A biosynhesis
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?
CDP + CoA
15.4% activity compared to ATP
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?
CTP + 3'-dephospho-CoA
CDP + CoA
7.3% activity compared to ATP
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?
GDP + CoA
32.6% activity compared to ATP
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?
GTP + 3'-dephospho-CoA
GDP + CoA
33% activity compared to ATP
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?
GTP + 3'-dephospho-CoA
GDP + CoA
gene TK1697 encodes a GTP-dependent dephospho-CoA kinase
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?
GTP + 3'-dephospho-CoA
GDP + CoA
gene TK1697 encodes a GTP-dependent dephospho-CoA kinase
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?
GTP + 3'-dephospho-CoA
GDP + CoA
gene TK1697 encodes a GTP-dependent dephospho-CoA kinase
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?
TDP + CoA
24.1% activity compared to ATP
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?
TTP + 3'-dephospho-CoA
TDP + CoA
4.9% activity compared to ATP
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?
UDP + CoA
2.6% activity compared to ATP
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?
UTP + 3'-dephospho-CoA
UDP + CoA
4.5% activity compared to ATP
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?
?
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assay method: arsenolysis of dephospho-CoA, formation of CoA
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additional information
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assay method: arsenolysis of dephospho-CoA, formation of CoA
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?
additional information
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when NADx02, ADP, AMP, adenosine, or ribose are substituted for dephospho-CoA as phosphate acceptors, no detectable amount of GDP is produced, indicating specificity of the TK1697 protein toward dephospho-CoA. GTP is the preferred phosphate donor
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additional information
?
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when NADx02, ADP, AMP, adenosine, or ribose are substituted for dephospho-CoA as phosphate acceptors, no detectable amount of GDP is produced, indicating specificity of the TK1697 protein toward dephospho-CoA. GTP is the preferred phosphate donor
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additional information
?
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when NADx02, ADP, AMP, adenosine, or ribose are substituted for dephospho-CoA as phosphate acceptors, no detectable amount of GDP is produced, indicating specificity of the TK1697 protein toward dephospho-CoA. GTP is the preferred phosphate donor
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-
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additional information
?
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when NADx02, ADP, AMP, adenosine, or ribose are substituted for dephospho-CoA as phosphate acceptors, no detectable amount of GDP is produced, indicating specificity of the TK1697 protein toward dephospho-CoA. GTP is the preferred phosphate donor
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