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2.7.1.23: NAD+ kinase

This is an abbreviated version!
For detailed information about NAD+ kinase, go to the full flat file.

Reaction

ATP
+
NAD+
=
ADP
+
NADP+

Synonyms

Afnk, AtNADK1, AtNADK2, AtNADK3, ATP: NAD(H) 2'-phosphotransferase, ATP:NAD 2'-phosphotransferase, ATP:NAD+ 2'-phosphotransferase, BsNADK, C5orf33, C5orf33 protein, diphosphopyridine nucleotide kinase, diphosphppyridine kinase, DPN kinase, EC 2.7.1.23, GmNADK1, GmNADK2, GmNADK3, GmNADK4, GmNADK5, HsNADK, kinase (phosphorylating), nicotinamide adenine dinucleotide, kinase, nicotinamide adenine dinucleotide (phosphorylating), MJ0917, NAD kinase, NAD kinase 1, NAD kinase 2, NAD kinase2, NAD(H) kinase, NadF, NADHK, NADK, NADK1, NADK2, NADK3, NADP phosphatase/NAD kinase, native plant calcium- and calmodulin-dependent NAD+-kinase, nicotinamide adenine dinucleotide kinase, OsNADK1, PH1074, Poly(P)/ATP NAD kinase , poly(P)/ATP-NAD kinase, poly(P)/ATPdependent NAD kinase, polyP/ATP-dependent NAD kinase, polyphosphate/ATP-NAD kinase, Pos5, Ppnk, PPNK_THEMA, sll1415, SlNADK1, SlNADK2, slr0040, slr0400, slr1415, SpNADK1, SpNADK2, styNadK, Utr, Utr1, Utr1p, YEF1, Yef1p, YfjB, YjbN, YtdI

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.23 NAD+ kinase

pH Stability

pH Stability on EC 2.7.1.23 - NAD+ kinase

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pH STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5
-
4°C, 18 h, about 60% loss of activity, irreversible loss of activity
641180
5.5
rapid inactivation below
641193
5.5 - 7
6 - 7
-
4°C, 18 h, stable
641180
7
Corynebacterium glutamicum subsp. lactofermentum
-
the enzyme remains stable at pH 7.0
722144
7 - 8
-
the enzyme is precipitated and denatured at pH 7.0. Even at pH 8.0, the enzyme is depolymerized and denatured after long-time storing
722144
8
-
4°C, 18 h, about 50% loss of activity, loss of activity is reversible by dialysis to pH 6.2
641180
8.5
-
4°C, 18 h, about 70% loss of activity, loss of activity is reversible by dialysis to pH 6.2
641180