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2.7.1.23: NAD+ kinase

This is an abbreviated version!
For detailed information about NAD+ kinase, go to the full flat file.

Reaction

ATP
+
NAD+
=
ADP
+
NADP+

Synonyms

Afnk, AtNADK1, AtNADK2, AtNADK3, ATP: NAD(H) 2'-phosphotransferase, ATP:NAD 2'-phosphotransferase, ATP:NAD+ 2'-phosphotransferase, BsNADK, C5orf33, C5orf33 protein, diphosphopyridine nucleotide kinase, diphosphppyridine kinase, DPN kinase, EC 2.7.1.23, GmNADK1, GmNADK2, GmNADK3, GmNADK4, GmNADK5, HsNADK, kinase (phosphorylating), nicotinamide adenine dinucleotide, kinase, nicotinamide adenine dinucleotide (phosphorylating), MJ0917, NAD kinase, NAD kinase 1, NAD kinase 2, NAD kinase2, NAD(H) kinase, NadF, NADHK, NADK, NADK1, NADK2, NADK3, NADP phosphatase/NAD kinase, native plant calcium- and calmodulin-dependent NAD+-kinase, nicotinamide adenine dinucleotide kinase, OsNADK1, PH1074, Poly(P)/ATP NAD kinase , poly(P)/ATP-NAD kinase, poly(P)/ATPdependent NAD kinase, polyP/ATP-dependent NAD kinase, polyphosphate/ATP-NAD kinase, Pos5, Ppnk, PPNK_THEMA, sll1415, SlNADK1, SlNADK2, slr0040, slr0400, slr1415, SpNADK1, SpNADK2, styNadK, Utr, Utr1, Utr1p, YEF1, Yef1p, YfjB, YjbN, YtdI

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.23 NAD+ kinase

pH Range

pH Range on EC 2.7.1.23 - NAD+ kinase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5.5 - 7.5
-
about 50% of maximal activity at pH 5.5 and pH 7.5
6 - 10
-
pH 6.0: about 40% of maximal activity, pH 10.0: about 80% of maximal activity
6 - 7
-
activity decreases sharply below pH 6.0 and above pH 7.0
6.5 - 7.2
-
90% of maximal activity at pH 6.5 and pH 7.2
6.5 - 9.5
-
pH 6.5: about 35% of maximal activity, pH 9.5: about 90% of maximal activity
6.8 - 9.2
-
90% of maximal activity between pH 6.8 and pH 9.2, 410000 Da Ca2+-calmodulin-independent isoform
7 - 10
-
pH 7.0: about 35% of maximal activity, pH 10.0: about 50% of maximal activity
7.2 - 8.5
-
90% of maximal activity between pH 7.2 and pH 8.5, 63000 Da Ca2+-calmodulin-dependent isoform
additional information
-
broad