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2.7.1.23: NAD+ kinase

This is an abbreviated version!
For detailed information about NAD+ kinase, go to the full flat file.

Reaction

ATP
+
NAD+
=
ADP
+
NADP+

Synonyms

Afnk, AtNADK1, AtNADK2, AtNADK3, ATP: NAD(H) 2'-phosphotransferase, ATP:NAD 2'-phosphotransferase, ATP:NAD+ 2'-phosphotransferase, BsNADK, C5orf33, C5orf33 protein, diphosphopyridine nucleotide kinase, diphosphppyridine kinase, DPN kinase, EC 2.7.1.23, GmNADK1, GmNADK2, GmNADK3, GmNADK4, GmNADK5, HsNADK, kinase (phosphorylating), nicotinamide adenine dinucleotide, kinase, nicotinamide adenine dinucleotide (phosphorylating), MJ0917, NAD kinase, NAD kinase 1, NAD kinase 2, NAD kinase2, NAD(H) kinase, NadF, NADHK, NADK, NADK1, NADK2, NADK3, NADP phosphatase/NAD kinase, native plant calcium- and calmodulin-dependent NAD+-kinase, nicotinamide adenine dinucleotide kinase, OsNADK1, PH1074, Poly(P)/ATP NAD kinase , poly(P)/ATP-NAD kinase, poly(P)/ATPdependent NAD kinase, polyP/ATP-dependent NAD kinase, polyphosphate/ATP-NAD kinase, Pos5, Ppnk, PPNK_THEMA, sll1415, SlNADK1, SlNADK2, slr0040, slr0400, slr1415, SpNADK1, SpNADK2, styNadK, Utr, Utr1, Utr1p, YEF1, Yef1p, YfjB, YjbN, YtdI

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.23 NAD+ kinase

Specific Activity

Specific Activity on EC 2.7.1.23 - NAD+ kinase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0009966
-
-
0.281
30°C, pH 8.0
0.5
-
substrates ATP, NAD+, mutant G208A, 37°C, pH 8.0
0.7
-
substrates ATP, NAD+, mutant S199A, 37°C, pH 8.0
1.1
-
substrates ATP, NAD+, mutant T195A, 37°C, pH 8.0
1.2
-
substrates ATP, NAD+, wild-type, 37°C, pH 8.0
1.4
-
pH 7.0, 37°C, substrate NAD+, cosubstrate poly(P)4, mutant G183R
1.78
-
pH 7.0, 37°C, substrate NAD+, cosubstrate ATP, mutant G183R
12.45
-
pH 7.0, 37°C, wild-type, substrate ATP
12.86
-
pH 7.0, 37°C, wild-type, substrate NAD+
18.67
-
pH 7.0, 37°C, substrate NAD+, cosubstrate ATP, wild-type
2.2
-
substrates polyphosphate, NAD+, mutant G208A, 37°C, pH 8.0
2.33
-
pH 7.0, 37°C, mutant R175G, substrate NAD+
2.5
-
substrates polyphosphate, NAD+, mutant S199A, 37°C, pH 8.0
2.68
-
pH 7.0, 37°C, mutant R175, substrate ATP
23.2
-
ATP-dependent activity
24.3
-
polyphosphate-dependent activity
3.5
-
substrates polyphosphate, NAD+, mutant T195A, 37°C, pH 8.0
3.8
-
substrates polyphosphate, NAD+, wild-type, 37°C, pH 8.0
3.84
-
activated by Ca2+-calmodulin
8.63
-
pH 7.0, 37°C, substrate NAD+, cosubstrate poly(P)4, wild-type