2.7.1.191: protein-Npi-phosphohistidine-D-mannose phosphotransferase

This is an abbreviated version!
For detailed information about protein-Npi-phosphohistidine-D-mannose phosphotransferase, go to the full flat file.

Reaction

Synonyms

CD2775, D-glucosaminate PTS permease component EIIA, D-glucosaminate PTS permease component EIIB, D-glucosaminate PTS permease component EIIC, D-glucosaminate PTS permease component EIID, dgaABCD, EC 2.7.1.69, EII, EII man, EII(t)Man, EIIABCDman, EIIMan, EIItMan, EIItMan phosphotransferase system permease, enzyme II, Enzyme II Man, enzyme IIMan, glucose/mannose-phosphotransferase system permease, II-AMan, II-BMan, II-MMan, II-PMan, IIAB protein, IIABLMan, IIABMan, IIAMan, IIAmannose, IIBMan, IIBmannose, IICMan, IICmannose, IIDMan, IIDmannose, IIIMan, IIMan, Man-PTS, man-PTS EII, ManA, ManB, ManC, manL, manLMN, manN, mannose enzyme II, mannose family phosphotransferase system permease, mannose permease, mannose permease IID, mannose phosphotransferase system, mannose PTS, mannose PTS permease, mannose transporter, mannose-specific Enzyme II, mannose-specific phosphotransferase system component IID, mannose-specific PTS, mannosyl-1-phosphotransferase, ManPT, manR, ManX, manXYZ, ManY, ManZ, MptA, MptC, MptD, permease IIC, phosphoenolpyruvate-dependent phosphotransferase system, protein enzyme II, ptnABCD, PTS permease, ptsL pel/ptsM, ptsLPM, ptsM

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.191 protein-Npi-phosphohistidine-D-mannose phosphotransferase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	Activating Compound
7138	AA Sequence
7	Cloned(Commentary)
3	Expression
24	General Information
3	Inhibitors
2	kcat/KM [mM/s]
6	KM Value [mM]
16	Localization
15	Molecular Weight [Da]
31	Natural Substrates/ Products (Substrates)
75	Organism
4	Pathway
1	Posttranslational Modification
9	Protein Variants
1	Purification (Commentary)
1	Reaction
41	Reference
1	Storage Stability
57	Substrates and Products (Substrate)
12	Subunits
134	Synonyms
1	Systematic Name
2	Turnover Number [1/s]

Systematic Name

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Systematic Name on EC 2.7.1.191 - protein-Npi-phosphohistidine-D-mannose phosphotransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Systematic Name Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SYSTEMATIC NAME

IUBMB Comments

protein-Npi-phospho-L-histidine:D-mannose Npi-phosphotransferase

This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it. The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9 (phosphoenolpyruvate---protein phosphotransferase). Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency. The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.