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2.7.1.190: aminoglycoside 2''-phosphotransferase

This is an abbreviated version!
For detailed information about aminoglycoside 2''-phosphotransferase, go to the full flat file.

Word Map on EC 2.7.1.190

Reaction

GTP
+
gentamicin
=
GDP
 +
gentamicin 2''-phosphate

Synonyms

AAC(6')-APH(2''), AAC(6')-Ie/APH(2'')-Ia, aac6-aph2, aacA-aphD, AME, aminoglycoside (2'') kinase, aminoglycoside 2''-phosphotransferase IVa, aminoglycoside 2''-phosphotransferase type IIIa, aminoglycoside kinase, aminoglycoside phosphotransferase, aminoglycoside-2''-phosphotransferase, aminoglycoside-2''-phosphotransferase type IVa, aminoglycoside-modification enzyme, APH, APH(2''), APH(2'')-Ia, APH(2'')-Ia aminoglycoside resistance enzyme, APH(2'')-Id, Aph(2'')-If, APH(2'')-IIIa, APH(2'')-IVa, aphD, AphSR2, bifunctional 6'-aminoglycoside acetyltransferase/2"-aminoglycoside phosphotransferase, bifunctional AAC/APH, bifunctional aminoglycoside acetyltransferase(6')-Ie/aminoglycoside phosphotransferase(2'')-Ia, bifunctional aminoglycoside acetyltransferase/phosphotransferase, gentamicin kinase, gentamicin phosphotransferase, gentamicin resistance protein

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.190 aminoglycoside 2''-phosphotransferase

Natural Substrates Products

Natural Substrates Products on EC 2.7.1.190 - aminoglycoside 2''-phosphotransferase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + kanamycin
ADP + kanamycin 2''-phosphate
show the reaction diagram
-
-
-
-
?
ATP + tobramycin
ADP + tobramycin 2''-phosphate
show the reaction diagram
-
-
-
-
?
GTP + amikacin
GDP + amikacin 2''-phosphate
show the reaction diagram
GTP + dibekacin
GDP + dibekacin 2''-phosphate
show the reaction diagram
-
-
-
-
?
GTP + gentamicin
GDP + gentamicin 2''-phosphate
show the reaction diagram
GTP + gentamicin C1
GDP + gentamicin C1 2''-phosphate
show the reaction diagram
-
-
-
?
GTP + hygromycin
GDP + hygromycin 2''-phosphate
show the reaction diagram
GTP + isepamycin
GDP + isepamycin 2''-phosphate
show the reaction diagram
-
-
-
-
?
GTP + kanamycin
GDP + kanamycin 2''-phosphate
show the reaction diagram
GTP + kanamycin A
GDP + kanamycin A 2''-phosphate
show the reaction diagram
-
-
-
?
GTP + lividomycin
GDP + lividomycin 2''-phosphate
show the reaction diagram
-
-
-
-
?
GTP + neomycin
GDP + neomycin 2''-phosphate
show the reaction diagram
GTP + neomycin B
GDP + neomycin B 2''-phosphate
show the reaction diagram
-
-
-
?
GTP + netilmycin
GDP + netilmycin 2''-phosphate
show the reaction diagram
-
-
-
-
?
GTP + ribostamycin
GDP + ribostamycin 2''-phosphate
show the reaction diagram
GTP + sisomycin
GDP + sisomycin 2''-phosphate
show the reaction diagram
-
-
-
-
?
GTP + streptomycin
GDP + streptomycin 2''-phosphate
show the reaction diagram
-
-
-
-
?
GTP + tobramycin
GDP + tobramycin 2''-phosphate
show the reaction diagram
additional information
?
-
GTP is the exclusive phosphate donor at intracellular nucleotide levels
-
-
?