2.7.1.190: aminoglycoside 2''-phosphotransferase

This is an abbreviated version!
For detailed information about aminoglycoside 2''-phosphotransferase, go to the full flat file.

Word Map on EC 2.7.1.190

2.7.1.190

aph3\'-iiia

kanamycin

enterococci

aac6\'-ie-aph2\'\'-ia

faecium

aminoglycoside-modifying

phosphotransferases

aph2\'\'-ic

amikacin

gentamicin-resistant

aac6\'-aph2

tobramycin

4,6-disubstituted

casseliflavus

aac6'-ie

ant6\'-ia

gallinarum

aminoglycoside-resistance

lividomycin

butirosin

o-phosphorylation

sisomicin

durans

molecular biology

Reaction

Synonyms

AAC(6')-APH(2''), AAC(6')-Ie/APH(2'')-Ia, aac6-aph2, aacA-aphD, AME, aminoglycoside (2'') kinase, aminoglycoside 2''-phosphotransferase IVa, aminoglycoside 2''-phosphotransferase type IIIa, aminoglycoside kinase, aminoglycoside phosphotransferase, aminoglycoside-2''-phosphotransferase, aminoglycoside-2''-phosphotransferase type IVa, aminoglycoside-modification enzyme, APH, APH(2''), APH(2'')-Ia, APH(2'')-Ia aminoglycoside resistance enzyme, APH(2'')-Id, Aph(2'')-If, APH(2'')-IIIa, APH(2'')-IVa, aphD, AphSR2, bifunctional 6'-aminoglycoside acetyltransferase/2"-aminoglycoside phosphotransferase, bifunctional AAC/APH, bifunctional aminoglycoside acetyltransferase(6')-Ie/aminoglycoside phosphotransferase(2'')-Ia, bifunctional aminoglycoside acetyltransferase/phosphotransferase, gentamicin kinase, gentamicin phosphotransferase, gentamicin resistance protein

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.190 aminoglycoside 2''-phosphotransferase

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Results	in table
264	AA Sequence
1	Application
7	Cloned(Commentary)
9	Cofactor
7	Crystallization (Commentary)
16	General Information
1	IC50 Value
38	Inhibitors
33	kcat/KM [mM/s]
11	Ki Value [mM]
38	KM Value [mM]
7	Metals/Ions
2	Molecular Weight [Da]
32	Natural Substrates/ Products (Substrates)
20	Organism
24	PDB ID
3	pH Optimum
10	Protein Variants
2	Purification (Commentary)
3	Reaction
17	Reference
70	Substrates and Products (Substrate)
4	Subunits
52	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
36	Turnover Number [1/s]

KI Value

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KI Value on EC 2.7.1.190 - aminoglycoside 2''-phosphotransferase

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0.14

butirosin A/B

Staphylococcus aureus

P0A0C1

pH 7.0, 22°C

734204

0.011 - 0.012

lividomycin A

2 entries

0.00016

neamine

Campylobacter jejuni

Q4VR94

pH 7.0, 22°C

733113

0.00026 - 0.00073

neomycin B

2 entries

0.0053 - 0.0085

paromomycin

2 entries

0.01761

quercetin

Staphylococcus aureus

P0A0C1

pH 7.5, 37°C

761726

0.074 - 0.085

ZINC13236811

2 entries