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2.7.1.189: autoinducer-2 kinase

This is an abbreviated version!
For detailed information about autoinducer-2 kinase, go to the full flat file.

Word Map on EC 2.7.1.189

Reaction

ATP
+
(S)-4,5-dihydroxypentane-2,3-dione
=
ADP
+
(S)-4-hydroxypentane-2,3-dione 5-phosphate

Synonyms

AI-2 kinase, AI-2 processing kinase, Lsr kinase, lsrK, LsrK kinase

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.189 autoinducer-2 kinase

IC50 Value

IC50 Value on EC 2.7.1.189 - autoinducer-2 kinase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.025
1,2-dihydroxydecane-3,4-dione
Salmonella enterica
-
pH and temperature not specified in the publication
0.0053
1,2-dihydroxyheptane-3,4-dione
Salmonella enterica
-
pH and temperature not specified in the publication
0.05
1,2-dihydroxyhexane-3,4-dione
Salmonella enterica
-
above, pH and temperature not specified in the publication
0.005
1,2-dihydroxyoctane-3,4-dione
Salmonella enterica
-
pH and temperature not specified in the publication
0.011 - 0.012
2,3,4,5-tetrachloro-6-(2,3,4,5-tetrachloroanilino)benzoic acid
0.032 - 0.07
2-(3-chloro-2-methylanilino)benzoic acid
0.023 - 0.119
2-(3-chloroanilino)benzoic acid
0.036 - 0.141
2-(4-chloroanilino)benzoic acid
0.02 - 0.03
2-anilino-4-chlorobenzoic acid
0.031 - 0.067
2-[2-chloro-5-(trifluoromethyl)anilino]-5-methoxybenzoic acid
0.003
7-deacetoxy-7-oxokhivorin
Salmonella enterica subsp. enterica serovar Typhimurium
pH 7.4, 22°C, recombinant enzyme
0.007
7-dehydroxypryogallin-4-carboxylic acid
Salmonella enterica subsp. enterica serovar Typhimurium
pH 7.4, 22°C, recombinant enzyme
0.004
acetyl isogambogic acid
Salmonella enterica subsp. enterica serovar Typhimurium
pH 7.4, 22°C, recombinant enzyme
0.007
Agaric acid
Salmonella enterica subsp. enterica serovar Typhimurium
pH 7.4, 22°C, recombinant enzyme
0.001
Aurin tricarboxylic acid
Salmonella enterica subsp. enterica serovar Typhimurium
pH 7.4, 22°C, recombinant enzyme
0.004
celastrol
Salmonella enterica subsp. enterica serovar Typhimurium
pH 7.4, 22°C, recombinant enzyme
0.007
fumarprotocetraric acid
Salmonella enterica subsp. enterica serovar Typhimurium
pH 7.4, 22°C, recombinant enzyme
0.01
harpagoside
Salmonella enterica subsp. enterica serovar Typhimurium
pH 7.4, 22°C, recombinant enzyme
0.009
protoporphyrin IX
Salmonella enterica subsp. enterica serovar Typhimurium
pH 7.4, 22°C, recombinant enzyme
0.001
rosolic acid
Salmonella enterica subsp. enterica serovar Typhimurium
pH 7.4, 22°C, recombinant enzyme
0.003
stictic acid
Salmonella enterica subsp. enterica serovar Typhimurium
pH 7.4, 22°C, recombinant enzyme
0.009
tetrachloroisophtalonitrile
Salmonella enterica subsp. enterica serovar Typhimurium
pH 7.4, 22°C, recombinant enzyme