2.7.1.189: autoinducer-2 kinase
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For detailed information about autoinducer-2 kinase, go to the full flat file.
Word Map on EC 2.7.1.189
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2.7.1.189
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quorum
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cell-cell
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interspecies
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repressor
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chemotaxis
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amp
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prevailing
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typhimurium
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envision
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quorum-sensing
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fight
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drug development
- 2.7.1.189
-
quorum
-
cell-cell
-
interspecies
- repressor
-
chemotaxis
- amp
-
prevailing
- typhimurium
-
envision
-
quorum-sensing
-
fight
- drug development
Reaction
Synonyms
AI-2 kinase, AI-2 processing kinase, Lsr kinase, lsrK, LsrK kinase
ECTree
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Engineering
Engineering on EC 2.7.1.189 - autoinducer-2 kinase
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additional information
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generation of chromosomal lsrK deletion (DELTAlsrK), or a chromosomal lsrRK double-deletion (DELTAlsrRK), the transcriptional activities of lsrR-P and lsrA-P do not differ significantly in the wild-type and lsrK-deficient backgrounds, while in the absence of LsrR, the transcriptional activity of both lsrR-P and lsrA-P is increased relative to that of the wild-type strain
additional information
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genomic deletion of gene lsrK. Genes lsrK and lsrR knockouts behave identically concerning the quantity and architecture of biofilms by affecting genes including flu and wza, small riboregulators respond to the QS regulators lsrR and lsrK, e.g. the sRNA cell division inhibitor DicF is induced by at least twofold in both lsrR and lsrK mutants. 117 and 32 genes are induced and repressed, respectively, by lsrK, transcriptosome analysis in enzyme mutants, overview
additional information
assembly of a capsule of biological polymers alginate and chitosan, with attached/encapsulated AI-2 processing kinase LsrK and provided substrate ATP, for the enzymatic alteration of AI-2 in culture fluids. The functionalized capsules, when introduced into populations of bacteria, alter the dynamics of the AI-2 bacterial communication, attenuating QS activated phenotypes. Method, overview
additional information
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construction of an in frame deletion of the lsrK gene, phenotype, overview
additional information
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construction of an in frame deletion of the lsrK gene, phenotype, overview
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