2.7.1.186: mevalonate-3-phosphate 5-kinase

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For detailed information about mevalonate-3-phosphate 5-kinase, go to the full flat file.

Reaction

Synonyms

M3P5K, MVA-3-P 5-kinase, Ta0762

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.186 mevalonate-3-phosphate 5-kinase

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Results	in table
3	AA Sequence
2	Cloned(Commentary)
16	General Information
1	KM Value [mM]
6	Natural Substrates/ Products (Substrates)
6	Organism
5	Pathway
2	pH Optimum
2	Purification (Commentary)
1	Reaction
6	Reference
7	Substrates and Products (Substrate)
16	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
3	Temperature Stability [°C]
1	Turnover Number [1/s]

KM Value

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KM Value on EC 2.7.1.186 - mevalonate-3-phosphate 5-kinase

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

additional information

(R)-3-phosphomevalonate

Thermoplasma acidophilum

Q9HK44

pH 8.0, 60°C, it is not possible to accurately determine the Km for mevalonate-3-phosphate-5-kinase, however, because the substrate is not commercially available and the detection limit of the assay is 0.03 mM substrate. The enzyme is still at Vmax when it is assayed with 0.06 mM mevalonate 3-phosphate, indicating that the Km is well below 0.06 mM

727046