2.7.1.185: mevalonate 3-kinase

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For detailed information about mevalonate 3-kinase, go to the full flat file.

Word Map on EC 2.7.1.185

2.7.1.185

acidophilum

thermoplasma

isopentenyl

isoprenoids

pyrophosphate

decarboxylases

picrophilus

archaea

torridus

cholesterol

synthesis

Reaction

Synonyms

ATP:(R)-MVA 3-phosphotransferase, M3K, mevalonate 3-kinase, mevalonate-3-kinase, More, PtM3K, PTO1356, Ta1305, TacM3K

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.185 mevalonate 3-kinase

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Results	in table
3	AA Sequence
2	Application
5	Cloned(Commentary)
3	Crystallization (Commentary)
44	General Information
7	kcat/KM [mM/s]
8	KM Value [mM]
1	Metals/Ions
20	Natural Substrates/ Products (Substrates)
66	Organism
5	Pathway
3	pH Optimum
1	pH Range
45	Protein Variants
4	Purification (Commentary)
6	Reaction
20	Reference
46	Substrates and Products (Substrate)
2	Subunits
53	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]
7	Turnover Number [1/s]

Cloned

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Cloned on EC 2.7.1.185 - mevalonate 3-kinase

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expression in Escherichia coli

3 entries

gene Ta1305, the pBAD-TacM plasmid series contains the genes of M3K, M3P5K, BMD, and IPK for the expression of part of modified MVA pathway II. Although the M3K, M3P5K, and IPK genes are derived from Thermoplasma acidophilum, various BMD genes have been utilized for plasmid construction. Recombinant expression of His-tagged enzyme in Escherichia coli strain BL21

Thermoplasma acidophilum

Q9HIN1

758668

recombinant expression of the PtM3K gene under a J23105 promoter

Picrophilus torridus

Q6KZB1

760079