Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.7.1.176: UDP-N-acetylglucosamine kinase

This is an abbreviated version!
For detailed information about UDP-N-acetylglucosamine kinase, go to the full flat file.

Word Map on EC 2.7.1.176

Reaction

ATP
+
UDP-N-acetyl-alpha-D-glucosamine
=
ADP
+
UDP-N-acetyl-alpha-D-glucosamine 3'-phosphate

Synonyms

epsilon/zeta toxin-antitoxin homologue, Ngzeta_1, ng_epsilon1 / ng_zeta1, ng_zeta1 toxin, PezT, TA homologue, toxin PezT, toxin zeta, UNAG kinase, zeta toxin, Zeta-toxin

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.176 UDP-N-acetylglucosamine kinase

Engineering

Engineering on EC 2.7.1.176 - UDP-N-acetylglucosamine kinase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D66T
-
site-directed mutagenesis, a nontoxicPezT variant, no bulge formation or lysis after induction of PezT D66T
K115A
site-directed mutagenesis, inactive mutant
D66T/W232Y
-
site-directed mutagenesis, a mutated tryptophan-free PezT variant
K45A
site-directed mutagenesis, the mutation abolishes PezT lethality
R157A
site-directed mutagenesis, the mutation abolishes PezT lethality
R170A
site-directed mutagenesis, the mutation abolishes PezT lethality
T117V
site-directed mutagenesis, the mutation abolishes PezT lethality
T120V
site-directed mutagenesis, the mutation abolishes PezT lethality and a delay in the growth inhibition
A111C
deletion of one A in the AAAAAAA tract, which begins at the 78-nt position, results in a frameshift and the stop codon formation after 51 codons, additional mutations are insertion of G after A32 and A111C substitution in one case and A248G substitution in the second one
A248G
deletion of one A in the AAAAAAA tract, which begins at the 78-nt position, results in a frameshift and the stop codon formation after 51 codons, additional mutations are insertion of G after A32 and A111C substitution in one case and A248G substitution in the second one
D66T
site-directed mutagenesis, a nontoxicPezT variant, no bulge formation or lysis after induction of PezT D66T
D67T
site-directed mutagenesis
K46A
site-directed mutagenesis, the change in the Walker A motif enables cloning and expression of genes K46A and D67T in Escherichia coli without coexpression of the antagonistic gene epsilon
K46A/D67T
site-directed mutagenesis, the change in the Walker A motif enables cloning and expression of genes K46A and D67T in Escherichia coli without coexpression of the antagonistic gene epsilon
R158A
site-directed mutagenesis, the mutant construct can be cloned into Escherichia coli but not overexpressed
R158A/R171S
site-directed mutagenesis, the mutant can be cloned and expressed
R171S
site-directed mutagenesis
additional information