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2.7.1.166: 3-deoxy-D-manno-octulosonic acid kinase

This is an abbreviated version!
For detailed information about 3-deoxy-D-manno-octulosonic acid kinase, go to the full flat file.

Word Map on EC 2.7.1.166

Reaction

3-deoxy-alpha-D-manno-oct-2-ulopyranosyl-(2->6)-2-deoxy-2-[[(3R)-3-hydroxytetradecanoyl]amino]-3-O-[(3R)-3-hydroxytetradecanoyl]-4-O-phosphono-beta-D-glucopyranosyl-(1->6)-2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-[[(3R)-3-hydroxytetradecanoyl]amino]-1-O-phosphono-alpha-D-glucopyranose
+
ATP
=
3-deoxy-4-O-phosphono-alpha-D-manno-oct-2-ulopyranosyl-(2->6)-2-deoxy-2-[[(3R)-3-hydroxytetradecanoyl]amino]-3-O-[(3R)-3-hydroxytetradecanoyl]-4-O-phosphono-beta-D-glucopyranosyl-(1->6)-2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-[[(3R)-3-hydroxytetradecanoyl]amino]-1-O-phosphono-alpha-D-glucopyranose
 +
ADP

Synonyms

3-deoxy-D-manno-octulosonic acid kinase, KdkA, Kdo kinase, Kdo kinase A

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.166 3-deoxy-D-manno-octulosonic acid kinase

Cloned

Cloned on EC 2.7.1.166 - 3-deoxy-D-manno-octulosonic acid kinase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
both Escherichia coli strains which express waaA and kdkA from Haemophilus influenzae synthesize an lipopolysaccharide containing a single Kdo residue that is exclusively phosphorylated at position 4
expression in Escherichia coli behind a T7 promoter, overproduction
gene kdkA, genotyping of clinical isolates