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2.7.1.165: glycerate 2-kinase

This is an abbreviated version!
For detailed information about glycerate 2-kinase, go to the full flat file.

Word Map on EC 2.7.1.165

Reaction

ATP
+
D-glycerate
=
ADP
 +
2-phospho-D-glycerate

Synonyms

2-PGA forming glycerate kinase, class II GK, class II glycerate kinase, D-glycerate 2-kinase, D-glycerate kinase, D-glycerate-2-kinase, EcoGK1, garK, GCK, glxK, glycerate kinase, glycerate kinase (2-phosphoglycerate forming), Glyctk, GLYK, More, slr1840, Sso-GK, SSO0666, SynGK, Ta0453, TM1585, TM_1585

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.165 glycerate 2-kinase

Inhibitors

Inhibitors on EC 2.7.1.165 - glycerate 2-kinase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(R)-glycerate
2,3-diphospho-D-glycerate
-
-
2-propanol
10% v/v, less than 65% inhibition; less than 65% activity in the presence of 10% (v/v)
3-phosphoglycerate
-
-
ATP
weak substrate inhibition
CuCl2
D-glycerate
substrate inhibition; substrate inhibition at glycerate concentrations higher than 2 mM at 80°C, above 2 mM at 70°C and 5 mM at 65°C
ethanol
10% v/v, less than 65% inhibition; less than 65% activity in the presence of 10% (v/v)
guanidine hydrochloride
85% residual activity at 1 M guanidine hydrochloride
HgCl2
Hydroxypyruvate
-
-
Mn2+
93% activity in the presence of 10 mM Mn2+ compared to Mg2+
n-butanol
10% v/v, less than 65% inhibition; less than 65% activity in the presence of 10% (v/v)
Ni2+
68% activity in the presence of 10 mM Ni2+ compared to Mg2+
p-chloromercuribenzoate
-
-
Phenylmethylsulfonylfluoride
less than 30% residual activity at 10 mM
PMSF
10 mM, more than 70% inhibition
SDS
10 mM, more than 60% inhibition; less than 40% residual activity at 10 mM
Sodium fluoride
65% residual activity at 1 M sodium fluoride
Sr2+
79% activity in the presence of 10 mM Sr2+ compared to Mg2+
Zn2+
84% activity in the presence of 10 mM Zn2+ compared to Mg2+
additional information
-