2.7.1.161: CTP-dependent riboflavin kinase
This is an abbreviated version!
For detailed information about CTP-dependent riboflavin kinase, go to the full flat file.
Reaction
Synonyms
CTP-dependent riboflavin kinase, Methanocaldococcus jannaschii Mj0056, MJ0056, myRbkR, pyRbkR, RbkR, RibK, riboflavin kinase, taRbkR
ECTree
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Inhibitors
Inhibitors on EC 2.7.1.161 - CTP-dependent riboflavin kinase
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the FMN-bound enzyme does not show myRbkR concentration-dependent binding with any tested DNA fragment, suggesting that FMN has a disruptive effect on DNA binding
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additional information
FAD does not show any significant effect on enzyme-DNA interaction, while riboflavin and FMN substantially diminish the DNA binding affinity. Half-maximal EC50 of riboflavin and FMN are calculated to 144 nM and 41 nM, respectively, showing that FMN has a greater negative effect on the DNA-protein interactions
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