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2.7.1.160: 2'-phosphotransferase

This is an abbreviated version!
For detailed information about 2'-phosphotransferase, go to the full flat file.

Word Map on EC 2.7.1.160

Reaction

2'-phospho-[ligated tRNA]
+
NAD+
=
mature tRNA
+
ADP-ribose 1'',2''-phosphate
+
nicotinamide

Synonyms

2'-phosphotransferase, ApeTpt1, AtPt, CTHT_0025470, HeLa cell 2'-phosphotransferase, human TRPT1, KptA, kptA1, mTPT1, NAD+-dependent 2'-phosphotransferase, NAD-dependent RNA 2'-phosphotransferase, RNA 2'-phosphotransferase, RslTpt1, Tpt1, Tpt1p, tRNA 2'-phosphotransferase, Trpt1, yeast 2'-phosphotransferase

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.160 2'-phosphotransferase

Inhibitors

Inhibitors on EC 2.7.1.160 - 2'-phosphotransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2'-fluoroarabinose
-
ApGpApUpUpUpApC
-
oligonucleotide, which lacks secondary structure and has no terminal phosphate
ara-2''F-NAD+
-
arabinose-2'-phosphate
-
Formamide
PS-2'-FANA oligonucleotides
-
phosphorothioate (PS) modifications of the 3'-5' phosphodiester backbone of DNA and 2'-FANA oligonucleotides (PS-DNA and PS-2'-FANA oligos) give substrates that are completely converted to 2'-hydroxy products by RslTpt1. Runella Tpt1 specific activity is reduced by 11fold and 7fold, respectively, by the PS modifications of DNA and 2'-FANA substrates
-
PS-DNA oligonucleotides
-
phosphorothioate (PS) modifications of the 3'-5'-phosphodiester backbone of DNA and 2'-FANA oligonucleotides (PS-DNA and PS-2'-FANA oligos) give substrates that are completely converted to 2'-hydroxy products by RslTpt1. Runella Tpt1 specific activity is reduced by 11fold and 7fold, respectively, by the PS modifications of DNA and 2'-FANA substrates
-
[pre-tRNA]
-
intron-containing yeast [pre-tRNA], which has the same structure as mature yeast [tRNA], except in the region of the intron
-
[tRNA]
-
mature Escherichia coli [tRNA], has canonical tRNA structue
-
additional information
-