2.7.1.158: inositol-pentakisphosphate 2-kinase

This is an abbreviated version!
For detailed information about inositol-pentakisphosphate 2-kinase, go to the full flat file.

Word Map on EC 2.7.1.158

2.7.1.158

hexakisphosphate

phytate

multikinase

1,2,3,4,5,6-hexakisphosphate

tetrakisphosphate

5/6-kinase

diagnostics

Reaction

1D-myo-inositol 1,3,4,5,6-pentakisphosphate

Synonyms

ASP1, At5g42810, AtIP5 2-K, AtIPK1, CnIpk1, Glyma04g03240, Glyma06g03310, GmIpk1, GmlPk1, Gsl1p, inositol 1,3,4,5,6-pentakis phosphate 2-kinase, inositol 1,3,4,5,6-pentakisphosphate 2-kinase, inositol hexakisphosphate kinase 1, inositol kinase, inositol pentakisphosphate 2-kinase, inositol polyphosphate kinase, inositol polyphosphate kinase-1, inositol polyphosphate kinase/phosphotransferase, inositol-1,3,4,5,6-pentakisphosphate 2-kinase, ins(1,3,4,5,6)P5 2-kinase, Ins5 2-kinase, InsP5 2-kinase, InsP6-kinase, IP5 2-K, IP5 2-kinase, IP5K, IP6K, IP6K1, Ipk1, Ipk1p, IPP2K, mIP5 2-K, Plc1p, rIPK1, scIpk1, spIpk1-C, StITPK1, StITPKalpha, ZmIPK1, ZmIPK1A, ZmIPK1B

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.158 inositol-pentakisphosphate 2-kinase

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Results	in table
3	Activating Compound
3687	AA Sequence
1	Application
1	CAS Registry Number
22	Cloned(Commentary)
11	Cofactor
4	Crystallization (Commentary)
31	Disease/ Diagnostics
32	General Information
2	General Stability
1	IC50 Value
11	Inhibitors
4	kcat/KM [mM/s]
33	KM Value [mM]
20	Localization
14	Metals/Ions
5	Molecular Weight [Da]
36	Natural Substrates/ Products (Substrates)
43	Organism
8	Pathway
37	PDB ID
8	pH Optimum
1	pH Range
2	pI Value
27	Protein Variants
15	Purification (Commentary)
1	Reaction
3	Reaction Type
39	Reference
70	Source Tissue
2	Specific Activity [micromol/min/mg]
1	Storage Stability
65	Substrates and Products (Substrate)
16	Subunits
108	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
1	Temperature Range [°C]
16	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 2.7.1.158 - inositol-pentakisphosphate 2-kinase

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(NH4)2SO4

Glycine max

slightly inhibitory

662093

1D-myo-inositol 1,4,6-trisphosphate

Schizosaccharomyces pombe

IC50: about 0.0007 mM. Potently reduces conversion of 1D-myo-inositol 1,4,5-trisphosphate to 1D-myo-inositol 1,4,5,6-tetrakisphosphate + 1D-myo-inositol 1,3,4,5-tetrakisphosphate

660942

5,6,7,8,4'-pentahydroxyflavone

Ca2+

20 mM, complete inhibition

chaetochromin

KCl

N2-(m-trifluoromethylbenzyl),N6-(p-nitrobenzyl)purine

2 entries

purpurogallin

Arabidopsis thaliana

Q93YN9

determination of ternary structure of AtIP5 2-K with purpurogallin and ADP, overview

761678

additional information

Arabidopsis thaliana

Q93YN9

high throughput screening of Arabidopsis thaliana inositol pentakisphosphate 2-kinase using an active site fluorescent probe, 2-FAM-InsP5 (2-O-(2-(5-fluoresceinylcarboxy)aminoethyl)-myo-inositol 1,3,4,5,6-pentakisphosphate (triethylammonium salt)), molecular docking calculations, overview

761678