2.7.1.156: adenosylcobinamide kinase

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For detailed information about adenosylcobinamide kinase, go to the full flat file.

Reaction

Synonyms

adenosylcobinamide kinase, adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase, AdoCbi kinase/AdoCbi-phosphate guanylyltransferase, ATP/GTP:AdoCbi kinase, bifunctional CobU enzyme, CobP, CobU, CobU AdoCbi kinase, CobU protein, GTP:adenosylcobinamide-phosphate guanylyltransferase, GTP:AdoCbi-P kinase, GTP:AdoCbi-phosphate guanylyltransferase, NTP:adenosylcobinamide kinase, NTP:AdoCbi kinase

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.156 adenosylcobinamide kinase

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Results	in table
1	Activating Compound
21074	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
4	Cofactor
3	Crystallization (Commentary)
1	General Stability
5	Inhibitors
2	KM Value [mM]
6	Molecular Weight [Da]
31	Natural Substrates/ Products (Substrates)
15	Organism
1	Oxidation Stability
6	Pathway
3	PDB ID
2	pH Optimum
1	pH Range
3	pI Value
4	Protein Variants
6	Purification (Commentary)
3	Reaction
2	Reaction Type
15	Reference
2	Source Tissue
5	Specific Activity [micromol/min/mg]
1	Storage Stability
56	Substrates and Products (Substrate)
4	Subunits
36	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Turnover Number [1/s]

Cloned

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Cloned on EC 2.7.1.156 - adenosylcobinamide kinase

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

A chromosomal in-frame deletion of the cobU gene is constructed in strain TR6583.

Salmonella enterica subsp. enterica serovar Typhimurium

-

674340

Chromosomal in-frame deletion mutations are constructed for the cobU gene using linear transformation and moved into strains with the deletion mutation apt-18, which causes strains to synthesize only pseudo-B12 cofactors.

Salmonella enterica subsp. enterica serovar Typhimurium

-

687405

gene cobU, DNA and amino acid sequence determination and analysis, overexpression in Escherichia coli strain BL21(DE3)

Salmonella enterica subsp. enterica serovar Typhimurium

-

663316

overexpressed

Salmonella enterica subsp. enterica serovar Typhimurium

-

651620

overexpressed in strain JE3207

Salmonella enterica subsp. enterica serovar Typhimurium

-

644435