Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
adipocyte
brenda
-
moderate expression of PI3K-C2alpha andPI3K-C2beta
brenda
-
brenda
-
moderate expression of PI3K-C2alpha
brenda
-
brenda
-
-
brenda
-
brenda
isozyme PI3K-C2beta is overexpressed in human breast cancer cell lines
brenda
-
low amount of isozyme p85, isozyme PI3K-C2beta and isozyme PI3K-C2alpha in bronchial epithelium
brenda
-
moderate expression of PI3K-C2alpha and PI3K-C2beta
brenda
-
of Fallopian tube, moderate expression of PI3K-C2alpha and weak expression of PI3K-C2beta
brenda
-
-
brenda
-
PI3K-C2alpha
brenda
-
moderate expression of PI3K-C2alpha and weak expression of PI3K-C2beta
brenda
high expression level of PI3KC2beta
brenda
-
isozyme PI3K-C2alpha, high amount of isozyme p85, and low amount of isozyme PI3K-C2beta
brenda
-
isozyme PI3K-C2alpha in smooth muscle layer, mononuclear cells, and lining epithelium, isozyme p85 and isozyme PI3K-C2beta in lining epithelium and mononuclear cells
brenda
-
strong expression of PI3K-C2alpha
brenda
-
brenda
-
brenda
-
-
brenda
-
strong expression of PI3K-C2alpha and moderate expression of PI3K-C2beta
brenda
-
isozyme p85, isozyme PI3K-C2beta and isozyme PI3K-C2alpha in alveolar macrophages
brenda
-
brenda
-
brenda
-
brenda
-
brenda
-
-
brenda
-
-
brenda
-
moderate expression of PI3K-C2alpha
brenda
-
non-myelinated, moderate expression of PI3K-C2beta
brenda
-
-
brenda
-
-
brenda
-
brenda
-
moderate expression of PI3K-C2alpha and PI3K-C2beta
brenda
expression at low level
brenda
-
brenda
-
brenda
-
isozyme PI3K-C2alpha inbasal epithelium and fibromuscular stroma, no isozyme PI3K-C2beta and isozyme p85
brenda
-
-
brenda
-
-
brenda
expression at low level
brenda
-
isozyme p85 in Langerhans cells, dermal macrophages, and in low amounts in sebaceous glands, hair follicles, and sweat gland, isozyme PI3K-C2beta and isozyme PI3K-C2alpha in dermal macrophages, low amount of isozyme PI3K-C2alpha in sweat gland
brenda
-
different cell lines overexpress different isozymes, e.g. cell lines H-69, HC-33, H-510, H-1045, and H-209
brenda
-
strong expression of PI3K-C2beta
brenda
-
brenda
-
isozyme PI3K-C2beta and isozyme PI3K-C2alpha, and high amount of isozyme p85 in peptic cells
brenda
-
brenda
-
isozyme PI3K-C2alpha in cervical smooth muscle, no isozyme PI3K-C2beta and isozyme p85
brenda
-
isozyme p85 in proliferative endometrium and in low amounts in secretory endometrium, isozyme PI3K-C2alpha in myometrium, no isozyme PI3K-C2beta
brenda
-
-
brenda
-
carcinoma-derived cell
brenda
-
carcinoma-derived cell
-
brenda
-
brenda
-
brenda
-
low amount of isozyme PI3K-C2alpha in myoepithelial cells and lactiferous ducts, no isozyme PI3K-C2beta and isozyme p85
brenda
PI3KC2gamma
brenda
non-neoplastic breast tissues
brenda
-
brenda
-
isozyme p85, isozyme PI3K-C2beta and isozyme PI3K-C2alpha in colonocytes
brenda
-
-
brenda
-
brenda
-
glomerular, PI3K-C2alpha
brenda
-
strong expression of PI3K-C2beta
brenda
-
high amounts of isozyme p85 and isozyme PI3K-C2beta
brenda
-
-
brenda
-
-
-
brenda
-
-
brenda
-
macrophage
brenda
expression at low level
brenda
-
mRNA is undetectable in kidney
brenda
-
isozyme p85 in glomerular macrophages, macula densa, and collecting tubules, high amount of isozyme PI3K-C2alpha in glomerular tuft, low amount of isozyme PI3K-C2beta and isozyme PI3K-C2alpha in proximal, distal, and collecting tubules
brenda
-
mRNA is undetectable in kidney
-
brenda
-
-
brenda
-
isozyme PI3K-C2alpha in bile ducts, no isozyme PI3K-C2beta and isozyme p85
brenda
PI3KC2gamma
brenda
exclusively expressed in liver
brenda
PI3K-IIgamma mRNA expression is confined to the liver throughout the development with much higher expression in adult liver than in fetal liver. Expression increases during liver regeneration after partial hepatectomy. PI3K-gamma may function mainly in highly differentiated hepatic cells
brenda
-
in the nuclear matrix harvested 20 h after partial hepatectomy, an increase in immunoprecipitable PI3K-C2beta activity is observed
brenda
-
brenda
-
weak expression of PI3K-C2alpha and PI3K-C2beta in germinal centre mononuclear cells, moderate expression of PI3K-C2alpha and PI3K-C2beta in tissue macrophages, strong expression of PI3K-C2alpha in polymorphonuclear leucocytes, weak expression of PI3K-C2alpha and moderate expression of PI3K-C2beta in medulla mononuclear cells, no expression in lymphoid follicles
brenda
-
isozyme p85 in medulla, germinal centre mononuclear cells, low amount in polymorphnuclear leucocytes, and high amount in tissue macrophages, isozyme PI3K-C2alpha and isozyme PI3K-C2beta in medulla, tissue macrophages, and germinal centre mononuclear cells, high amount of isozyme PI3K-C2alpha in polymorphnuclear leucocytes
brenda
PI3K-C2beta is highly expressed in lymph-nodes metastases compared to matching primary tumors
brenda
-
dermal, moderate expression of PI3K-C2alpha and PI3K-C2beta
brenda
-
glomerular, moderate expression of PI3K-C2beta
brenda
-
PI3K-C2alpha and PI3K-C2beta
brenda
-
isozyme PI3K-C2beta
brenda
-
cell culture
brenda
-
cell culture, cell line J774.2
brenda
-
-
brenda
-
brenda
-
moderate expression of PI3K-C2alpha and strong expression of PI3K-C2beta
brenda
-
all isozymes
brenda
-
brenda
PI3K class IIbeta (PI3KC2beta) and its regulator intersectin 1 (ITSN1) are highly expressed in primary neuroblastoma tumors and cell lines
brenda
-
-
brenda
-
isozyme p85, low amount of isozyme PI3K-C2beta and isozyme PI3K-C2alpha in follicular cells
brenda
-
-
-
brenda
-
brenda
-
moderate expression of PI3K-C2alpha and PI3K-C2beta
brenda
low enzyme expression
brenda
-
high amount of isozyme p85 in acini, isozyme PI3K-C2alpha in acini and ducts, no isozyme PI3K-C2beta
brenda
-
-
brenda
highest expression in thymus and placenta
brenda
-
-
-
brenda
-
fibromuscular stroma, moderate expression of PI3K-C2alpha
brenda
PI3KC2gamma
brenda
-
moderate expression of PI3K-C2alpha and weak expression of PI3K-C2beta
brenda
-
isozyme PI3K-C2alpha, high amount of isozyme p85, and low amount of isozyme PI3K-C2beta in enterocytes, isozyme p85 in Paneth cells
brenda
-
bronchial and cervical, moderate expression of PI3K-C2alpha
brenda
-
isozyme PI3K-C2alpha
brenda
-
strong expression of PI3K-C2alpha in red pulp splenic sinusoids, weak expression of PI3K-C2alpha and moderate expression of PI3K-C2beta in red pulp mononuclear cells, no expression in white pulp
brenda
-
isozyme p85, isozyme PI3K-C2beta and isozyme PI3K-C2alpha in red pulp
brenda
-
-
brenda
-
high content of isozyme p85 and isozyme PI3K-C2beta in spermatogenic cells, high content of isozyme PI3K-C2alpha in Leydig cells, isozyme p85 and PI3K-C2beta in Leydig cells
brenda
-
-
-
brenda
-
monocyte
brenda
-
monocyte
-
brenda
highest expression in thymus and placenta
brenda
high activity of PI3KC2beta
brenda
-
-
brenda
-
monocyte
brenda
monocyte
brenda
-
monocyte
-
brenda
-
brenda
HUVEC
brenda
-
moderate expression of PI3K-C2alpha and weak expression of PI3K-C2beta
brenda
-
isozyme PI3K-C2alpha in muscularis and transitional epithelium, isozyme p85 and isozyme PI3K-C2beta in transitional epithelium
brenda
additional information
-
isozyme expression pattern and phenotype, Drk adaptor protein might be involved in localization of the isozymes, overview
brenda
additional information
-
immunohistological analysis, no expression of isozymes in endocrine pancreas, thyroid, or parathyroid, topographical expression of class IA and class II isozymes in normal human tissues is consistent with a role in differentiation
brenda
additional information
widely expressed, but not ubiquitous
brenda
additional information
widely expressed, but not ubiquitous
brenda
additional information
widely expressed, but not ubiquitous
brenda
additional information
PI3KC2alpha is broadly expressed in human cells
brenda
additional information
PI3KC2alpha is broadly expressed in human cells
brenda
additional information
PI3KC2alpha is broadly expressed in human cells
brenda
additional information
isozyme PI3KC2alpha is widely expressed in mammalian cells
brenda