2.7.1.148: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase

This is an abbreviated version!
For detailed information about 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase, go to the full flat file.

Word Map on EC 2.7.1.148

2.7.1.148

isoprenoids

mevalonate

isopentenyl

malaria

2-phosphate

antimalarial

dimethylallyl

plasmodium

non-mevalonate

jasmonate

drug development

1-deoxy-d-xylulose

terpenoids

nonhydrolyzable

solvent-mediated

mevalonate-independent

gametocytic

apicomplexan

water-mediated

2,4-cyclodiphosphate

2-hydroxyl

dmapp

medicine

Reaction

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

Synonyms

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase, 4-(cytidine-5-diphospho)-2-C-methyl-D-erythritol kinase, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, 4-diphosphocytidyl-2-C-methylerythritol 2-kinase, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-kinase, 4-diphosphocytidyl-2C-methyl-D-erythritol kinase, AaIspE, BsIspE, CcCMK1, CDP-ME, CDP-ME kinase, CDP-methylerythritol kinase, CDPME kinase, CDPMEK, CMK, EcIspE, GbCMK1, GbCMK2, IspDF, IspE, More, PvIspE, Ripening-associated protein pTOM41, TwCMK, YchB

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.148 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase

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Results	in table
2	Activating Compound
35710	AA Sequence
5	Application
1	CAS Registry Number
13	Cloned(Commentary)
9	Cofactor
8	Crystallization (Commentary)
1	Expression
16	General Information
8	IC50 Value
19	Inhibitors
11	Ki Value [mM]
4	KM Value [mM]
5	Localization
16	Metals/Ions
6	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
128	Organism
7	Pathway
24	PDB ID
3	pH Optimum
4	pI Value
13	Protein Variants
10	Purification (Commentary)
5	Reaction
4	Reaction Type
27	Reference
4	Source Tissue
4	Specific Activity [micromol/min/mg]
33	Substrates and Products (Substrate)
5	Subunits
68	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Synonyms

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Synonyms on EC 2.7.1.148 - 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase

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4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase

4 entries

4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase

4-(cytidine-5-diphospho)-2-C-methyl-D-erythritol kinase

Tripterygium wilfordii

739765

4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

4 entries

4-diphosphocytidyl-2-C-methylerythritol 2-kinase

4-diphosphocytidyl-2C-methyl-D-erythritol 2-kinase

4-diphosphocytidyl-2C-methyl-D-erythritol kinase

AaIspE

BsIspE

CcCMK1

CDP-ME

CDP-ME kinase

CDP-methylerythritol kinase

Escherichia coli

699633

CDPME kinase

4 entries

CDPMEK

CMK

EcIspE

GbCMK1

Isoenzyme with 433 amino acids. The identity between GbCMK2 and GbCMK1 is 62.7%.

689692

GbCMK2

Ginkgo biloba

A6XAA9

isoenzyme with 428 amino acids. The identity between GbCMK2 and GbCMK1 is 62.7%.

689692

IspDF

Agrobacterium tumefaciens

in Agrobacterium tumefaciens the ispD and ispF genes are fused to encode a bifunctional enzyme that catalyzes the first (synthesis of 4-diphosphocytidyl-2-C-methyl D-erythritol) and third (synthesis of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate) steps of isoprenoid biosynthetic pathway

672138

IspE

8 entries

PvIspE

2 entries

Ripening-associated protein pTOM41

TwCMK

Tripterygium wilfordii

YchB

additional information

3 entries