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2.7.1.147: ADP-specific glucose/glucosamine kinase

This is an abbreviated version!
For detailed information about ADP-specific glucose/glucosamine kinase, go to the full flat file.

Word Map on EC 2.7.1.147

Reaction

ADP
+
D-glucosamine
=
AMP
+
D-glucosamine 6-phosphate

Synonyms

ADP-dependent glucokinase, ADP-dependent hexokinase, ADP-dependent kinase, ADP-GK, ADP-HK, ADP-Pfk, ADP-specific glucokinase, ADP:D-glucose 6-phosphotransferase, ADPGK, ancGK/PFK, AncMsPFK/GK, bifunctional ADP-dependent phosphofructokinase/glucokinase, GlcN kinase, glucosamine kinase, MevePFK/GK, MjPFK/GK, MmazPFK/GK, MmPFK/GK, More, NagC4, pfGK, pfkC, PhPFK, TK1110, tlGK

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.147 ADP-specific glucose/glucosamine kinase

Reference

Reference on EC 2.7.1.147 - ADP-specific glucose/glucosamine kinase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kengen, S.W.M.; Tuininga, J.E.; de Bok, F.A.M.; Stams, A.J.M.; de Vos, W.M.
Purification and characterization of a novel ADP-dependent glucokinase from the hyperthermophilic archaeon Pyrococcus furiosus
J. Biol. Chem.
270
30453-30457
1995
Pyrococcus furiosus
Manually annotated by BRENDA team
Ito, S.; Fushinobu, S.; Yoshioka, I.; Koga, S.; Matsuzawa, H.; Wakagi, T.
Structural basis for the ADP-specificity of a novel glucokinase from a hyperthermophilic archaeon
Structure
9
205-214
2001
Thermococcus litoralis (Q7M537), Thermococcus litoralis
Manually annotated by BRENDA team
Kengen, S.W.M.; Tuininga, J.E.; Verhees, C.H.; Van der Oost, J.; Stams, A.J.M.; De Vos, W.M.
ADP-dependent glucokinase and phosphofructokinase from Pyrococcus furiosus
Methods Enzymol.
331
41-53
2001
Pyrococcus furiosus
Manually annotated by BRENDA team
Koga, S.; Yoshioka, I.; Sakuraba, H.; Takahashi, M.; Sakasegawa, S.; Shimizu, S.; Ohshima, T.
Biochemical characterization, cloning, and sequencing of ADP-dependent (AMP-forming) glucokinase from two hyperthermophilic archaea, Pyrococcus furiosus and Thermococcus litoralis
J. Biochem.
128
1079-1085
2000
Pyrococcus furiosus, Thermococcus litoralis
Manually annotated by BRENDA team
Sakuraba, H.; Yoshioka, I.; Koga, S.; Takahashi, M.; Kitahama, Y.; Satomura, T.; Kawakami, R.; Ohshima, T.
ADP-dependent glucokinase/phosphofructokinase, a novel bifunctional enzyme from the hyperthermophilic archaeon Methanococcus jannaschii
J. Biol. Chem.
277
12495-12498
2002
Methanocaldococcus jannaschii
Manually annotated by BRENDA team
Verhees, C.H.; Koot, D.G.; Ettema, T.J.; Dijkema, C.; De Vos, W.M.; Van Der Oost, J.
Biochemical adaptations of two sugar kinases from the hyperthermophilic archaeon Pyrococcus furiosus
Biochem. J.
366
121-127
2002
Pyrococcus furiosus (Q9V2Z6), Pyrococcus furiosus
Manually annotated by BRENDA team
Labes, A.; Schonheit, P.
ADP-dependent glucokinase from the hyperthermophilic sulfate-reducing archaeon Archaeoglobus fulgidus strain 7324
Arch. Microbiol.
180
69-75
2003
Archaeoglobus fulgidus, Archaeoglobus fulgidus 7324
Manually annotated by BRENDA team
Ronimus, R.S.; Morgan, H.W.
Cloning and biochemical characterization of a novel mouse ADP-dependent glucokinase
Biochem. Biophys. Res. Commun.
315
652-658
2004
Mus musculus (Q8VDL4), Mus musculus
Manually annotated by BRENDA team
Ito, S.; Fushinobu, S.; Jeong, J.J.; Yoshioka, I.; Koga, S.; Shoun, H.; Wakagi, T.
Crystal structure of an ADP-dependent glucokinase from Pyrococcus furiosus: implications for a sugar-induced conformational change in ADP-dependent kinase
J. Mol. Biol.
331
871-883
2003
Pyrococcus furiosus (Q9V2Z6), Pyrococcus furiosus
Manually annotated by BRENDA team
Tsuge, H.; Sakuraba, H.; Kobe, T.; Kujime, A.; Katunuma, N.; Ohshima, T.
Crystal structure of the ADP-dependent glucokinase from Pyrococcus horikoshii at 2.0-A resolution: a large conformational change in ADP-dependent glucokinase
Protein Sci.
11
2456-2463
2002
Pyrococcus horikoshii, Pyrococcus horikoshii OT-3
Manually annotated by BRENDA team
Labes, A.; Schoenheit, P.
Sugar utilization in the hyperthermophilic, sulfate-reducing archaeon Archaeoglobus fulgidus strain 7324: starch degradation to acetate and CO2 via a modified Embden-Meyerhof pathway and acetyl-CoA synthetase (ADP-forming)
Arch. Microbiol.
176
329-338
2001
Archaeoglobus fulgidus, Archaeoglobus fulgidus 7324
Manually annotated by BRENDA team
Merino, F.; Rivas-Pardo, J.A.; Caniuguir, A.; Garcia, I.; Guixe, V.
Catalytic and regulatory roles of divalent metal cations on the phosphoryl-transfer mechanism of ADP-dependent sugar kinases from hyperthermophilic archaea
Biochimie
94
516-524
2012
Pyrococcus furiosus, Pyrococcus horikoshii, Thermococcus litoralis
Manually annotated by BRENDA team
Kaminski, M.M.; Sauer, S.W.; Kaminski, M.; Opp, S.; Ruppert, T.; Grigaravinius, P.; Grudnik, P.; Groene, H.J.; Krammer, P.H.; Guelow, K.
T cell activation is driven by an ADP-dependent glucokinase linking enhanced glycolysis with mitochondrial reactive oxygen species generation
Cell Rep.
2
1300-1315
2012
Homo sapiens
Manually annotated by BRENDA team
Kengen, S.W.; de Bok, F.A.; van Loo, N.D.; Dijkema, C.; Stams, A.J.; de Vos, W.M.
Evidence for the operation of a novel Embden-Meyerhof pathway that involves ADP-dependent kinases during sugar fermentation by Pyrococcus furiosus
J. Biol. Chem.
269
17537-17541
1994
Pyrococcus furiosus
Manually annotated by BRENDA team
Richter, S.; Richter, J.P.; Mehta, S.Y.; Gribble, A.M.; Sutherland-Smith, A.J.; Stowell, K.M.; Print, C.G.; Ronimus, R.S.; Wilson, W.R.
Expression and role in glycolysis of human ADP-dependent glucokinase
Mol. Cell. Biochem.
364
131-145
2012
Homo sapiens
Manually annotated by BRENDA team
Castro-Fernandez, V.; Bravo-Moraga, F.; Herrera-Morande, A.; Guixe, V.
Bifunctional ADP-dependent phosphofructokinase/glucokinase activity in the order Methanococcales - biochemical characterization of the mesophilic enzyme from Methanococcus maripaludis
FEBS J.
281
2017-2029
2014
Methanococcus maripaludis (Q6LXQ3), Methanococcus maripaludis
Manually annotated by BRENDA team
Rivas-Pardo, J.A.; Herrera-Morande, A.; Castro-Fernandez, V.; Fernandez, F.J.; Vega, M.C.; Guixe, V.
Crystal structure, SAXS and kinetic mechanism of hyperthermophilic ADP-dependent glucokinase from Thermococcus litoralis reveal a conserved mechanism for catalysis
PLoS One
8
e66687
2013
Thermococcus litoralis (Q7M537), Thermococcus litoralis, Thermococcus litoralis DSM 5473 (Q7M537)
Manually annotated by BRENDA team
Qian, Z.; Zhao, J.; Bai, X.; Tong, W.; Chen, Z.; Wei, H.; Wang, Q.; Liu, S.
Thermal stability of glucokinases in Thermoanaerobacter tengcongensis
BioMed Res. Int.
2013
646539
2013
Caldanaerobacter subterraneus subsp. tengcongensis (Q8R8N4), Caldanaerobacter subterraneus subsp. tengcongensis DSM 15242 (Q8R8N4)
Manually annotated by BRENDA team
Abarca-Lagunas, M.J.; Rivas-Pardo, J.A.; Ramirez-Sarmiento, C.A.; Guixe, V.
Dissecting the functional roles of the conserved NXXE and HXE motifs of the ADP-dependent glucokinase from Thermococcus litoralis
FEBS Lett.
589
3271-3276
2015
Thermococcus litoralis (Q7M537), Thermococcus litoralis, Thermococcus litoralis DSM 5473 (Q7M537)
Manually annotated by BRENDA team
Richter, J.P.; Goroncy, A.K.; Ronimus, R.S.; Sutherland-Smith, A.J.
The Structural and functional characterization of mammalian ADP-dependent glucokinase
J. Biol. Chem.
291
3694-3704
2016
Homo sapiens (Q9BRR6)
Manually annotated by BRENDA team
Richter, S.; Morrison, S.; Connor, T.; Su, J.; Print, C.G.; Ronimus, R.S.; McGee, S.L.; Wilson, W.R.
Zinc finger nuclease mediated knockout of ADP-dependent glucokinase in cancer cell lines: effects on cell survival and mitochondrial oxidative metabolism
PLoS ONE
8
e65267
2013
Homo sapiens
Manually annotated by BRENDA team
Ito, S.; Fushinobu, S.; Yoshioka, I.; Koga, S.; Matsuzawa, H.; Wakagi, T.
Structural basis for the ADP-specificity of a novel glucokinase from a hyperthermophilic archaeon
Structure
9
205-214
2001
Thermococcus litoralis (Q7M537), Thermococcus litoralis, Thermococcus litoralis DSM 5473 (Q7M537)
Manually annotated by BRENDA team
Aslam, M.; Takahashi, N.; Matsubara, K.; Imanaka, T.; Kanai, T.; Atomi, H.
Identification of the glucosamine kinase in the chitinolytic pathway of Thermococcus kodakarensis
J. Biosci. Bioeng.
125
320-326
2018
Thermococcus kodakarensis, Thermococcus kodakarensis (Q5JE39), Thermococcus kodakarensis ATCC BAA-918 (Q5JE39)
Manually annotated by BRENDA team
Zamora, R.; Gonzalez-Órdenes, F.; Castro-Fernández, V.; Guixé, V.
ADP-dependent phosphofructokinases from the archaeal order Methanosarcinales display redundant glucokinase activity
Arch. Biochem. Biophys.
633
85-92
2017
Methanohalobium evestigatum (D7E8P3), Methanohalobium evestigatum, Methanococcoides burtonii (Q12WB9), Methanococcoides burtonii, Methanococcoides burtonii OCM 468 (Q12WB9), Methanococcoides burtonii ACE-M (Q12WB9), Methanococcoides burtonii NBRC 107633 (Q12WB9), Methanohalobium evestigatum DSM 3721 (D7E8P3), Methanohalobium evestigatum OCM 161 (D7E8P3), Methanohalobium evestigatum Z-7303 (D7E8P3), Methanohalobium evestigatum ATCC BAA-1072 (D7E8P3), Methanohalobium evestigatum NBRC 107634 (D7E8P3), Methanococcoides burtonii DSM 6242 (Q12WB9)
Manually annotated by BRENDA team
Gonzalez-Ordenes, F.; Cea, P.A.; Fuentes-Ugarte, N.; Munoz, S.M.; Zamora, R.A.; Leonardo, D.; Garratt, R.C.; Castro-Fernandez, V.; Guixe, V.
ADP-dependent kinases from the archaeal order Methanosarcinales adapt to salt by a non-canonical evolutionarily conserved strategy
Front. Microbiol.
9
1305
2018
uncultured bacterium, Methanohalobium evestigatum (D7E8P3), Methanosarcina mazei (Q8PZL9), Methanosarcina mazei OCM 88 (Q8PZL9), Methanosarcina mazei DSM 3647 (Q8PZL9), Methanosarcina mazei Goe1 (Q8PZL9), Methanosarcina mazei JCM 11833 (Q8PZL9), Methanohalobium evestigatum DSM 3721 (D7E8P3), Methanohalobium evestigatum OCM 161 (D7E8P3), Methanohalobium evestigatum Z-7303 (D7E8P3), Methanohalobium evestigatum ATCC BAA-1072 (D7E8P3), Methanohalobium evestigatum NBRC 107634 (D7E8P3), Methanosarcina mazei ATCC BAA-159 (Q8PZL9)
Manually annotated by BRENDA team
Castro-Fernandez, V.; Herrera-Morande, A.; Zamora, R.; Merino, F.; Gonzalez-Ordenes, F.; Padilla-Salinas, F.; Pereira, H.M.; Brandao-Neto, J.; Garratt, R.C.; Guixe, V.
Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases
J. Biol. Chem.
292
15598-15610
2017
uncultured bacterium, Methanocaldococcus jannaschii (Q58999), Thermococcus litoralis (Q7M537), Methanocaldococcus jannaschii ATCC 43067 (Q58999), Thermococcus litoralis ATCC 51850 (Q7M537)
Manually annotated by BRENDA team
Grudnik, P.; Kaminski, M.M.; Rembacz, K.P.; Kuska, K.; Madej, M.; Potempa, J.; Dawidowski, M.; Dubin, G.
Structural basis for ADP-dependent glucokinase inhibition by 8-bromo-substituted adenosine nucleotide
J. Biol. Chem.
293
11088-11099
2018
Pyrococcus horikoshii (O58328), Homo sapiens (Q9BRR6), Homo sapiens, Pyrococcus horikoshii ATCC 700860 (O58328)
Manually annotated by BRENDA team
Tokarz, P.; Wisniewska, M.; Kaminski, M.M.; Dubin, G.; Grudnik, P.
Crystal structure of ADP-dependent glucokinase from Methanocaldococcus jannaschii in complex with 5-iodotubercidin reveals phosphoryl transfer mechanism
Protein Sci.
27
790-797
2018
Methanocaldococcus jannaschii (Q58999), Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661 (Q58999)
Manually annotated by BRENDA team
Tandon, A.; Birkenhagen, J.; Nagalla, D.; Koelker, S.; Sauer, S.W.
ADP-dependent glucokinase as a novel onco-target for haematological malignancies
Sci. Rep.
10
13584
2020
Homo sapiens (Q9BRR6)
Manually annotated by BRENDA team
Imle, R.; Wang, B.T.; Stuetzenberger, N.; Birkenhagen, J.; Tandon, A.; Carl, M.; Himmelreich, N.; Thiel, C.; Groene, H.J.; Poschet, G.; Voelkers, M.; Guelow, K.; Schroeder, A.; Carillo, S.; Mittermayr, S.; Bones, J.; Kaminski, M.M.; Koelker, S.; Sauer, S.W.
ADP-dependent glucokinase regulates energy metabolism via ER-localized glucose sensing
Sci. Rep.
9
14248
2019
Danio rerio, Homo sapiens (Q9BRR6)
Manually annotated by BRENDA team