2.7.1.147: ADP-specific glucose/glucosamine kinase

This is an abbreviated version!
For detailed information about ADP-specific glucose/glucosamine kinase, go to the full flat file.

Reaction

Synonyms

ADP-dependent glucokinase, ADP-dependent hexokinase, ADP-dependent kinase, ADP-GK, ADP-HK, ADP-Pfk, ADP-specific glucokinase, ADP:D-glucose 6-phosphotransferase, ADPGK, ancGK/PFK, AncMsPFK/GK, bifunctional ADP-dependent phosphofructokinase/glucokinase, GlcN kinase, glucosamine kinase, MevePFK/GK, MjPFK/GK, MmazPFK/GK, MmPFK/GK, More, NagC4, pfGK, pfkC, PhPFK, TK1110, tlGK

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.147 ADP-specific glucose/glucosamine kinase

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Results	in table
4	Activating Compound
195	AA Sequence
1	CAS Registry Number
27	Cloned(Commentary)
12	Cofactor
15	Crystallization (Commentary)
26	Disease/ Diagnostics
62	General Information
2	General Stability
3	IC50 Value
34	Inhibitors
43	kcat/KM [mM/s]
28	Ki Value [mM]
71	KM Value [mM]
4	Localization
77	Metals/Ions
14	Molecular Weight [Da]
50	Natural Substrates/ Products (Substrates)
144	Organism
1	Oxidation Stability
8	Pathway
16	PDB ID
22	pH Optimum
4	pH Range
24	Protein Variants
24	Purification (Commentary)
3	Reaction
1	Reaction Type
75	Reference
28	Source Tissue
13	Specific Activity [micromol/min/mg]
138	Substrates and Products (Substrate)
12	Subunits
141	Synonyms
1	Systematic Name
18	Temperature Optimum [°C]
7	Temperature Stability [°C]
42	Turnover Number [1/s]

Disease

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Disease on EC 2.7.1.147 - ADP-specific glucose/glucosamine kinase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Burkitt Lymphoma

ADP-dependent glucokinase as a novel onco-target for haematological malignancies.

32788680

Colonic Neoplasms

Liposomes Encapsulating Neoantigens and Black Phosphorus Quantum Dots for Enhancing Photothermal Immunotherapy.

33419493

Lung Neoplasms

[Differential expression of genes that encode glycolysis enzymes in kidney and lung cancer in humans].

24450150

Neoplasm Metastasis

Integrative analysis of mutational and transcriptional profiles reveals driver mutations of metastatic breast cancers.

27625789

Neoplasms

ADP-dependent glucokinase as a novel onco-target for haematological malignancies.

32788680

Neoplasms

Expression and role in glycolysis of human ADP-dependent glucokinase.

22219026

Neoplasms

Integrative analysis of mutational and transcriptional profiles reveals driver mutations of metastatic breast cancers.

27625789

Neoplasms

Structural basis for ADP-dependent glucokinase inhibition by 8-bromo-substituted adenosine nucleotide.

29784881

Neoplasms

The Structural and Functional Characterization of Mammalian ADP-dependent Glucokinase.

26555263

Neoplasms

Zinc finger nuclease mediated knockout of ADP-dependent glucokinase in cancer cell lines: effects on cell survival and mitochondrial oxidative metabolism.

23799003

Neoplasms

[Differential expression of genes that encode glycolysis enzymes in kidney and lung cancer in humans].

24450150

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