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2.7.1.138: ceramide kinase

This is an abbreviated version!
For detailed information about ceramide kinase, go to the full flat file.

Word Map on EC 2.7.1.138

Reaction

ATP
+
ceramide
=
ADP
+
ceramide 1-phosphate

Synonyms

acylsphingosine kinase, ceramide kinase, CERK, DCERK protein, hCERK, kinase, acylsphingosine (phosphorylating), More

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.138 ceramide kinase

Application

Application on EC 2.7.1.138 - ceramide kinase

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
analysis
enzymatic assay to quantify mass levels of long chain ceramides in cellular lipid extracts
diagnostics
-
putative prognostic marker in breast cancer, estrogen receptor negative patients with high ceramide kinase expression had a worse prognosis then those with low expression
medicine