2.7.1.137: phosphatidylinositol 3-kinase

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For detailed information about phosphatidylinositol 3-kinase, go to the full flat file.

Reaction

Synonyms

class 3 phosphatidylinositol 3-kinase vacuolar protein sorting 34, class I phosphoinositide 3-kinase, class III phosphatidylinositol 3-kinase, class III phosphoinositide 3-kinase, class III PI3K, HsC2-PI3K, hVps34, hVps34 PI 3-kinase, kinase (phosphorylating), phosphatidylinositol 3-, kinase, phosphatidylinositol 3- (phosphorylating), lipid kinase Vps34, mammalian vacuolar protein sorting 34 homologue, More, p110a, p110delta I PI3K., p110g-related PI 3-kinase, p85/p110 phosphoinositide 3-kinase, p85/p110 type phosphatidylinositol kinase, p85a phosphoinositide 3-kinase, phosphatidyl-inositol-3-kinase, phosphatidylinositide 3-kinase, phosphatidylinositide 3-kinase C2alpha, phosphatidylinositol 3 kinase, phosphatidylinositol 3'-kinase, phosphatidylinositol 3-kinase, phosphoinositide 3'-kinase, phosphoinositide 3-kinase, phosphoinositide 3-kinase Dp110, phosphoinositide 3-kinase gamma, phosphoinositide-3-kinase, PI 3-K, PI 3-kinase, PI-3-K, PI-3K, PI3 K, PI3 kinase, PI3-K, PI3-K-related protein MEC1, PI3-kinase, PI3K, PI3K type III, PI3Kalpha, PI3Kbeta, PI3Kgamma, PI3K_59F, PI3K_68D, PIK3, PIK3C3, protein sorting mutant 34 protein, PtdIns 3'-kinase, PtdIns 3-kinase, PtdIns 3-kinase vacuolar protein sorting 34, receptor-linked phosphatidylinositol 3-kinase, Rickettsia intracellular secreted kinase-1, Risk1, RT0135, TcVps34, type III phosphatidylinositol 3-kinase, vacuolar protein sorting 34, VPS34, Vps34p

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.137 phosphatidylinositol 3-kinase

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Results	in table
60	Activating Compound
3803	AA Sequence
17	Application
1	CAS Registry Number
40	Cloned(Commentary)
45	Cofactor
4	Crystallization (Commentary)
28436	Disease/ Diagnostics
2	Expression
97	General Information
22	IC50 Value
207	Inhibitors
3	Ki Value [mM]
16	KM Value [mM]
59	Localization
35	Metals/Ions
39	Molecular Weight [Da]
133	Natural Substrates/ Products (Substrates)
878	Organism
3	Pathway
81	PDB ID
15	pH Optimum
1	pH Range
14	Posttranslational Modification
52	Protein Variants
16	Purification (Commentary)
1	Reaction
1	Reaction Type
258	Reference
290	Source Tissue
13	Specific Activity [micromol/min/mg]
298	Substrates and Products (Substrate)
32	Subunits
209	Synonyms
1	Systematic Name
12	Temperature Optimum [°C]

Expression

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Expression on EC 2.7.1.137 - phosphatidylinositol 3-kinase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

downregulation of PI3K activity accelerates leaf senescence induced by methyl jasmonate (MeJA) and suppresses the activation of vacuolar H+-ATPase (VATPase)

Arabidopsis thaliana

P42339

762179

expression of PI3K in seed increases with the prolongation of imbibition time

Oryza sativa

-

723554