2.7.1.106: glucose-1,6-bisphosphate synthase

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For detailed information about glucose-1,6-bisphosphate synthase, go to the full flat file.

Reaction

Synonyms

glucose 1,6-diphosphate synthase, glucose-1,6-bisphosphate synthetase, PGM2L1, phosphoglucomutase 2

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.106 glucose-1,6-bisphosphate synthase

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Results	in table
38	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
3	Disease/ Diagnostics
30	Inhibitors
11	KM Value [mM]
2	Localization
13	Metals/Ions
2	Natural Substrates/ Products (Substrates)
4	Organism
2	Pathway
1	pH Optimum
1	pH Range
3	Purification (Commentary)
1	Reaction
1	Reaction Type
4	Reference
6	Source Tissue
2	Specific Activity [micromol/min/mg]
14	Substrates and Products (Substrate)
4	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Substrates Products

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Substrates Products on EC 2.7.1.106 - glucose-1,6-bisphosphate synthase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate

3-phospho-D-glycerate + D-glucose 1,6-bisphosphate

9 entries

3-phospho-D-glyceroyl phosphate + D-glucose 6-phosphate

3-phospho-D-glycerate + D-glucose 1,6-bisphosphate

2 entries

3-phospho-D-glyceroyl phosphate + D-mannose 1-phosphate

3-phospho-D-glycerate + D-mannose 1,6-bisphosphate

2 entries

3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate

3-phospho-D-glycerate + D-glucose 1,6-bisphosphate

Bos taurus

-

-

640349, 640350

-

-

r

3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate

3-phospho-D-glycerate + D-glucose 1,6-bisphosphate

Bos taurus

-

i.e. 1,3-diphosphoglycerate

640349

-

-

r

3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate

3-phospho-D-glycerate + D-glucose 1,6-bisphosphate

Bos taurus

-

specific for 3-phospho-D-glyceroyl phosphate

640349

-

-

r

3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate

3-phospho-D-glycerate + D-glucose 1,6-bisphosphate

Bos taurus

-

no acceptor activity mannose 6-phosphate

640349

-

-

r

3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate

3-phospho-D-glycerate + D-glucose 1,6-bisphosphate

Mus musculus

-

i.e. 1,3-diphosphoglycerate

640348

-

-

r

3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate

3-phospho-D-glycerate + D-glucose 1,6-bisphosphate

Mus musculus

-

no phosphoryl donors are acetyl phosphate, ATP, phosphoenolpyruvate, creatine phosphate, fructose 1,6-diphosphate

640348

-

-

r

3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate

3-phospho-D-glycerate + D-glucose 1,6-bisphosphate

Mus musculus

-

little or no acceptor activity: glucose, glucose 6-sulfate, glucosamine 6-phosphate, 2-deoxy-glucose 6-phosphate, 3-phosphoglycerate, galactose or fructose monophosphates

640348

-

-

r

3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate

3-phospho-D-glycerate + D-glucose 1,6-bisphosphate

Mus musculus

-

no acceptor activity mannose 6-phosphate

640348

-

-

r

3-phospho-D-glyceroyl phosphate + D-glucose 1-phosphate

3-phospho-D-glycerate + D-glucose 1,6-bisphosphate

Mus musculus

-

responsible for glucose 1,6-diphosphate biosynthesis in brain

640348

-

-

r

3-phospho-D-glyceroyl phosphate + D-glucose 6-phosphate

3-phospho-D-glycerate + D-glucose 1,6-bisphosphate

Bos taurus

-

-

640349

-

-

?

3-phospho-D-glyceroyl phosphate + D-glucose 6-phosphate

3-phospho-D-glycerate + D-glucose 1,6-bisphosphate

Mus musculus

-

phosphorylation at 56% the rate of glucose 1-phosphate

640348

-

-

?

3-phospho-D-glyceroyl phosphate + D-mannose 1-phosphate

3-phospho-D-glycerate + D-mannose 1,6-bisphosphate

Bos taurus

-

-

640349

-

-

?

3-phospho-D-glyceroyl phosphate + D-mannose 1-phosphate

3-phospho-D-glycerate + D-mannose 1,6-bisphosphate

Mus musculus

-

phosphorylation at 81% the rate of glucose 1-phosphate

640348

-

-

?