2.7.1.1: hexokinase

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For detailed information about hexokinase, go to the full flat file.

Reaction

Synonyms

6-phosphate glucose kinase, AtHXK1, ATP-D-hexose 6-phosphotransferase, ATP-D-hexose-6-phosphotransferase, ATP-dependent hexokinase, ATP: D-glucose 6-phosphotransferase, ATP: D-hexose 6-phosphotransferase, ATP:D-glucose 6-phosphotransferase, ATP:D-hexose 6-phosphotransferase, BmHk, brain form hexokinase, CzHXK1, FgHXK1, FgHXK2, GCK, GK, GKbeta, GlcK, glk, GlkB, glucokinase, glucokinase 1, glucokinase B, glucose ATP phosphotransferase, HaHXK1, hexokinase, hexokinase (phosphorylating), hexokinase 1, hexokinase 2, hexokinase 3, hexokinase 6, hexokinase A, hexokinase D, hexokinase Dor, hexokinase I, hexokinase II, hexokinase III, hexokinase IV, hexokinase PI, hexokinase PII, hexokinase type I, hexokinase type II, hexokinase type IV, hexokinase type IV glucokinase, hexokinase, tumor isozyme, hexokinase-1, hexokinase-10, hexokinase-2, hexokinase-4, hexokinase-5, hexokinase-6, hexokinase-7, hexokinase-8, hexokinase-9, hexokinase-II, hexokinase-like 1, hGK, hGK isoform 1, HK, HK II, HK-1, HK-I, HK-R, HK1, HK2, HK4, HKDC1, HKI, HKII, HKIII, HKL1, HPGLK1, HXK, HXK A, HXK II, Hxk1, HXK10, Hxk2, Hxk3, HXK4, HXK5, HXK6, HXK7, HXK8, HXK9, hxkC, hxkD, kinase, hexo- (phosphorylating), KlHxk1, LGK, LGK2, liver glucokinase, liver glucokinase isoform 2, MODY2 glucokinase, More, muscle form hexokinase, NfGlck, NtHXK1, OsHXK, OsHXK1, OsHXK10, OsHXK2, OsHXK3, OsHXK4, OsHXK5, OsHXK6, OsHXK7, OsHXK9, pHXK, plastid hexokinase, PpHXK1, PpHXK10, PpHXK11, PpHXK2, PpHXK3, PpHXK4, PpHXK5, PpHXK6, PpHXK7, PpHXK8, PpHXK9, Rag5p, ROK hexokinase, ScHK2, ScHXK2, SoHXK1, StHK, STK_23540, StoHK, TbHK1, TbHK2, TcHK, TthHK, type II hexokinase, VIT_18s0001g14230, xprF, Zm.5206, Zm.95484

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.1 hexokinase

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Results	in table
276	Activating Compound
5054	AA Sequence
24	Application
1	CAS Registry Number
90	Cloned(Commentary)
127	Cofactor
24	Crystallization (Commentary)
4640	Disease/ Diagnostics
19	Expression
78	General Information
32	General Stability
86	IC50 Value
392	Inhibitors
15	kcat/KM [mM/s]
162	Ki Value [mM]
500	KM Value [mM]
105	Localization
58	Metals/Ions
117	Molecular Weight [Da]
91	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
366	Organism
28	Pathway
92	PDB ID
74	pH Optimum
19	pH Range
6	pH Stability
32	pI Value
9	Posttranslational Modification
244	Protein Variants
108	Purification (Commentary)
15	Reaction
1	Reaction Type
322	Reference
351	Source Tissue
133	Specific Activity [micromol/min/mg]
15	Storage Stability
615	Substrates and Products (Substrate)
96	Subunits
328	Synonyms
1	Systematic Name
64	Temperature Optimum [°C]
4	Temperature Range [°C]
24	Temperature Stability [°C]
135	Turnover Number [1/s]

Temperature Range

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Temperature Range on EC 2.7.1.1 - hexokinase

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TEMPERATURE RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

25

Entamoeba histolytica

-

HXK1: 40% of maximum activity, HXK2: 28% of maximum activity

640266

30 - 47

Eimeria tenella

-

-

94720

30 - 90

Thermus caldophilus

Q5RLG0

weak activity at 30°C, high activity at 90°C, rapid decrease in activity above 90°C

660912

37

Entamoeba histolytica

-

HXK1: 78% of maximum activity, HXK2: 69% of maximum activity

640266