2.6.99.3: O-ureido-L-serine synthase
This is an abbreviated version!
For detailed information about O-ureido-L-serine synthase, go to the full flat file.
Reaction
Synonyms
DcsD
ECTree
2.6.99.3 O-ureido-L-serine synthaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 2.6.99.3 - O-ureido-L-serine synthase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
O-acetyl-L-serine + hydroxyurea
O-ureido-L-serine + acetate
-
-
-
?
O-acetyl-L-serine + hydroxyurea
O-ureido-L-serine + acetate
-
-
-
-
?
O-acetyl-L-serine + hydroxyurea
O-ureido-L-serine + acetate
the enzyme participates in the biosynthetic pathway of D-cycloserine, an antibiotic substance produced by several Streptomyces species
-
-
?
O-acetyl-L-serine + hydroxyurea
O-ureido-L-serine + acetate
O-ureido-L-serine i.e. (2S)-2-amino-3-[(carbamoylamino)oxy]propanoate
-
-
?
O-acetyl-L-serine + hydroxyurea
O-ureido-L-serine + acetate
O-ureido-L-serine i.e. (2S)-2-amino-3-[(carbamoylamino)oxy]propanoate. No activity with O3-acetyl-D-serine and L-serine. The enzyme prefers sulfide as the second substrate, followed by hydroxyurea, L-homocysteine, and thiosulfate. The enzyme also catalyzes the reaction with O-acetyl-L-serine and hydrogen sulfide (with 80fold higher catalytic efficiency)
-
-
?
O-acetyl-L-serine + hydroxyurea
O-ureido-L-serine + acetate
the enzyme participates in the biosynthetic pathway of D-cycloserine, an antibiotic substance produced by several Streptomyces species
-
-
?
O-acetyl-L-serine + hydroxyurea
O-ureido-L-serine + acetate
O-ureido-L-serine i.e. (2S)-2-amino-3-[(carbamoylamino)oxy]propanoate. No activity with O3-acetyl-D-serine and L-serine. The enzyme prefers sulfide as the second substrate, followed by hydroxyurea, L-homocysteine, and thiosulfate. The enzyme also catalyzes the reaction with O-acetyl-L-serine and hydrogen sulfide (with 80fold higher catalytic efficiency)
-
-
?
O-acetyl-L-serine + hydroxyurea
O-ureido-L-serine + acetate
-
-
-
?
O-acetyl-L-serine + hydroxyurea
O-ureido-L-serine + acetate
the enzyme participates in the biosynthetic pathway of D-cycloserine, an antibiotic substance produced by several Streptomyces species
-
-
?
O-acetyl-L-serine + hydroxyurea
O-ureido-L-serine + acetate
O-ureido-L-serine i.e. (2S)-2-amino-3-[(carbamoylamino)oxy]propanoate
-
-
?
O-acetyl-L-serine + hydroxyurea
O-ureido-L-serine + acetate
-
-
-
?
additional information
?
-
enzyme additionally catalyzes the formation of L-cysteine from O-acetyl-L-serine and H2S, reaction of EC 2.5.1.47
-
-
?
additional information
?
-
enzyme additionally catalyzes the formation of L-cysteine from O-acetyl-L-serine and H2S, reaction of EC 2.5.1.47. The kcat/Km value of DcsD for L-cysteine synthesis is 80fold higher than that for O-ureido-L-serine synthesis
-
-
?
additional information
?
-
-
enzyme additionally catalyzes the formation of L-cysteine from O-acetyl-L-serine and H2S, reaction of EC 2.5.1.47. The kcat/Km value of DcsD for L-cysteine synthesis is 80fold higher than that for O-ureido-L-serine synthesis
-
-
?
additional information
?
-
enzyme additionally catalyzes the formation of L-cysteine from O-acetyl-L-serine and H2S, reaction of EC 2.5.1.47. The kcat/Km value of DcsD for L-cysteine synthesis is 80fold higher than that for O-ureido-L-serine synthesis
-
-
?
additional information
?
-
enzyme additionally catalyzes the formation of L-cysteine from O-acetyl-L-serine and H2S, reaction of EC 2.5.1.47
-
-
?
