2.6.99.3: O-ureido-L-serine synthase

This is an abbreviated version!
For detailed information about O-ureido-L-serine synthase, go to the full flat file.

Reaction

Synonyms

DcsD

ECTree

     2 Transferases

         2.6 Transferring nitrogenous groups

             2.6.99 Transferring other nitrogenous groups

                2.6.99.3 O-ureido-L-serine synthase

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Results	in table
12	AA Sequence
2	Application
2	Cloned(Commentary)
1	Cofactor
1	Crystallization (Commentary)
8	kcat/KM [mM/s]
3	KM Value [mM]
2	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
20	Organism
6	Pathway
10	PDB ID
2	pH Optimum
1	pH Range
6	Protein Variants
1	Purification (Commentary)
1	Reaction
8	Reference
16	Substrates and Products (Substrate)
4	Subunits
5	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
3	Turnover Number [1/s]

Engineering

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Engineering on EC 2.6.99.3 - O-ureido-L-serine synthase

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PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

K43A

Streptomyces lavendulae

D2Z027

mutation in invariant Lys43 residue, inactive. Mutant forms an external aldimine adduct upon addition of L-methionine or O-ureido-L-serine

738218

S121A

Streptomyces lavendulae

D2Z027

decreased activity for synthesis of ureido-L-serine, increased activity for synthesis of L-cysteine

738218

S121M

Streptomyces lavendulae

D2Z027

decreased activity for synthesis of ureido-L-serine, increased activity for synthesis of L-cysteine

738218

V74T

Streptomyces lavendulae

D2Z027

decreased activity for synthesis of ureido-L-serine, increased activity for synthesis of L-cysteine

738218

Y97F

Streptomyces lavendulae

D2Z027

decreased activity for synthesis of ureido-L-serine, increased activity for synthesis of L-cysteine

738218

Y97M

Streptomyces lavendulae

D2Z027

decreased activity for synthesis of ureido-L-serine, increased activity for synthesis of L-cysteine

738218