2.6.99.1: dATP(dGTP)-DNA purinetransferase
This is an abbreviated version!
For detailed information about dATP(dGTP)-DNA purinetransferase, go to the full flat file.
Reaction
ECTree
2.6.99.1 dATP(dGTP)-DNA purinetransferaseAdvanced search results
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Substrates Products on EC 2.6.99.1 - dATP(dGTP)-DNA purinetransferase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
dATP + depurinated poly(dA-dT)
deoxyribose triphosphate + purinated poly(dA-dT)
-
dGTP cannot act as substrate
-
?
dGTP + depurinated poly(dG-dC)
deoxyribose triphosphate + purinated poly(dG-dC)
-
dATP cannot act as substrate
-
?
dTTP + depurinated DNA
deoxyribose triphosphate + purinated DNA
-
lower activity than that of dATP and dGTP, incorporation is supressed in the presence of dATP
-
?
dATP + depurinated DNA
deoxyribose triphosphate + purinated DNA
-
closed circular PM2 phage DNA, linear T7 phage DNA or Escherichia coli DNA can act as substrate
-
?
dATP + depurinated DNA
deoxyribose triphosphate + purinated DNA
-
closed circular PM2 phage DNA, linear T7 phage DNA or Escherichia coli DNA can act as substrate
-
?
dGTP + depurinated DNA
deoxyribose triphosphate + purinated DNA
-
closed circular PM2 phage DNA, linear T7 phage DNA or Escherichia coli DNA can act as substrate
-
?
dGTP + depurinated DNA
deoxyribose triphosphate + purinated DNA
-
closed circular PM2 phage DNA, linear T7 phage DNA or Escherichia coli DNA can act as substrate
-
?
additional information
?
-
-
specific insertion of adenine into adenine apurinic sites and guanine into guanine apurinic sites
-
-
?
additional information
?
-
-
enzyme does not act on depurinated single-stranded DNA
-
-
?
additional information
?
-
-
may represent a step in a repair mechanism, i.e. base-insertion repair, whereby apurinic sites, which may occur in double-stranded DNA either due to the removal of damaged purines with specific glycosylases or by spontaneous depurination, are directly filled with the correct missing purine base
-
-
?
additional information
?
-
-
specific insertion of adenine into adenine apurinic sites and guanine into guanine apurinic sites
-
-
?
