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2.6.1.B6: dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose transaminase

This is an abbreviated version!
For detailed information about dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose transaminase, go to the full flat file.

Reaction

dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose
+
2-oxoglutarate
=
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose
+
L-glutamate

Synonyms

DesI

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.B6 dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose transaminase

Crystallization

Crystallization on EC 2.6.1.B6 - dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose transaminase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
hanging drop method of vapor diffusion. The structure of DesI is solved in complex with its product, dTDP-4-amino-4,6-dideoxyglucose, to a nominal resolution of 2.1 A. Each subunit of the dimeric enzyme contains 12 alpha-helices and 14 alpha-strands. Crystals belong to the space group P2(1)2(1)2(1) with unit cell dimensions of 59.5 A, 66.8 A, 242.0 A and one dimer per asymmetric unit. Crystal dimensions are typically 1 mm * 0.6 mm * 0.2 mm