2.6.1.B3: aminopentol:pyruvate aminotransferase FumI

This is an abbreviated version!
For detailed information about aminopentol:pyruvate aminotransferase FumI, go to the full flat file.

Reaction

Synonyms

aminopentol:pyruvate aminotransferase, aminotransferase for deamination of hydrolyzed fumonisin B1 (gene fumI), aminotransferase FumI, dhf1, FumI, HFB1 deaminating activity

ECTree

     2 Transferases

         2.6 Transferring nitrogenous groups

             2.6.1 Transaminases

                2.6.1.B3 aminopentol:pyruvate aminotransferase FumI

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Results	in table
1	Activating Compound
2	AA Sequence
1	Application
4	Cloned(Commentary)
3	Cofactor
1	Inhibitors
3	KM Value [mM]
3	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
4	Organism
3	pH Optimum
1	pH Range
1	pH Stability
1	pI Value
2	Purification (Commentary)
1	Reaction
4	Reference
1	Specific Activity [micromol/min/mg]
1	Storage Stability
7	Substrates and Products (Substrate)
2	Subunits
7	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
1	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 2.6.1.B3 - aminopentol:pyruvate aminotransferase FumI

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

(2S,3S,5R,10S,12R,14R,15S,16S)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + oxaloacetate

(3S,5R,10S,12R,14R,15S,16S)-3,5,10,14,15-pentahydroxy-12,16-dimethylicosan-2-one + L-aspartate

Sphingopyxis sp.

-

-

724058

-

-

?

(2S,3S,5R,10S,12R,14R,15S,16S)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + pyruvate

(3S,5R,10S,12R,14R,15S,16S)-3,5,10,14,15-pentahydroxy-12,16-dimethylicosan-2-one + L-alanine

6 entries

(2S,3S,5R,10S,12R,14R,15S,16S)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + pyruvate

(3S,5R,10S,12R,14R,15S,16S)-3,5,10,14,15-pentahydroxy-12,16-dimethylicosan-2-one + L-alanine

bacterium ATCC 55552

E2E0Q4

the enzyme is involved in degradation of fumonisin B1. Fumonisin B1 is a mycotoxin produced by different phytopathogenic filamentous fungi

707601

-

-

?

(2S,3S,5R,10S,12R,14R,15S,16S)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + pyruvate

(3S,5R,10S,12R,14R,15S,16S)-3,5,10,14,15-pentahydroxy-12,16-dimethylicosan-2-one + L-alanine

bacterium ATCC 55552

E2E0Q4

recombinant aminotransferase is able to deaminate HFB1 in the presence of pyruvate and pyridoxal 5'-phosphate

707601

-

-

?

(2S,3S,5R,10S,12R,14R,15S,16S)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + pyruvate

(3S,5R,10S,12R,14R,15S,16S)-3,5,10,14,15-pentahydroxy-12,16-dimethylicosan-2-one + L-alanine

Sphingopyxis macrogoltabida

D2D3B2

(2S,3S,5R,10S,12R,14R,15S,16S)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol i.e. aminopentoln

709199

-

-

?

(2S,3S,5R,10S,12R,14R,15S,16S)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + pyruvate

(3S,5R,10S,12R,14R,15S,16S)-3,5,10,14,15-pentahydroxy-12,16-dimethylicosan-2-one + L-alanine

Sphingopyxis macrogoltabida

D2D3B2

(2S,3S,5R,10S,12R,14R,15S,16S)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol i.e. aminopentol, i.e. hydrolyzed fumonisin B1. The enzyme is independent of oxygen

709199

-

-

?

(2S,3S,5R,10S,12R,14R,15S,16S)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + pyruvate

(3S,5R,10S,12R,14R,15S,16S)-3,5,10,14,15-pentahydroxy-12,16-dimethylicosan-2-one + L-alanine

Sphingopyxis sp.

-

-

725883

-

-

?

(2S,3S,5R,10S,12R,14R,15S,16S)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + pyruvate

(3S,5R,10S,12R,14R,15S,16S)-3,5,10,14,15-pentahydroxy-12,16-dimethylicosan-2-one + L-alanine

Sphingopyxis sp.

-

activity observed with glyoxylate and 2-oxobutyrate, no activity detectable with 2-oxogluarate, substrates hydrolyzed fumonisin B2 and B3 also used

724058

-

-

?