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2.6.1.99: L-tryptophan-pyruvate aminotransferase

This is an abbreviated version!
For detailed information about L-tryptophan-pyruvate aminotransferase, go to the full flat file.

Word Map on EC 2.6.1.99

Reaction

L-tryptophan
+
pyruvate
=
Indole-3-pyruvate
+
L-alanine

Synonyms

At1g80360, F5I6.11, FIB, SAV3, TAA, TAA1, tryptophan aminotransferase of Arabidopsis, tryptophan aminotransferase of Arabidopsis 1, TRYPTOPHAN AMINOTRANSFERASE OF ARABIDOPSIS1, Vas1, vl2

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.99 L-tryptophan-pyruvate aminotransferase

Inhibitors

Inhibitors on EC 2.6.1.99 - L-tryptophan-pyruvate aminotransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(2S)-2-(aminooxy)-3-(naphthalen-2-yl)propanoic acid
competitive. Arabidopsis thaliana seedlings treated with the compound show typical auxin-deficient phenotypes, which are reversed by exogenous indole-3-acetic acid
L-alpha-aminooxy-phenylpropionic acid
target compound for inhibitor synthesis
L-kynurenine
additional information
synthesis of inhibitors based on L-alpha-aminooxy-phenylpropionic acid. The aminooxy and carboxy groups of the compound are essential for inhibition of TAA1 in vitro. Inhibitory activity of the compounds is correlated with their binding energy with TAA1. The active compounds reduce the endogenous indole-3-acetic acid content upon application to Arabidopsis thaiana seedlings
-