2.6.1.9: histidinol-phosphate transaminase
This is an abbreviated version!
For detailed information about histidinol-phosphate transaminase, go to the full flat file.
Word Map on EC 2.6.1.9
-
2.6.1.9
-
aminotransferases
-
5'-phosphate
-
auxotrophic
-
transamination
-
aldimine
-
plp-dependent
-
pyridoxamine
- 2.6.1.9
- aminotransferases
- 5'-phosphate
-
auxotrophic
-
transamination
-
aldimine
-
plp-dependent
- pyridoxamine
Reaction
Synonyms
aminotransferase, histidinol phosphate, AtHPA1, glutamic-imidazoleacetol phosphate transaminase, HisC, HisC2, histidine:imidazoleacetol phosphate transaminase, histidinol phosphate aminotransferase, histidinol-phosphate aminotransferase, HspAT, IAP transaminase, imidazoleacetol phosphate transaminase, imidazolylacetolphosphate aminotransferase, imidazolylacetolphosphate transaminase, L-histidinol phosphate aminotransferase, Rv1600
ECTree
2.6.1.9 histidinol-phosphate transaminaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 2.6.1.9 - histidinol-phosphate transaminase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
3-(4-hydroxyphenyl)-2-oxopropanoate + L-glutamate
L-tyrosine + 2-oxoglutarate
-
-
-
?
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-2-aminoadipate
L-histidinol phosphate + 2-oxoadipate
-
40% of the activity with L-glutamate
-
-
r
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-arginine
L-histidinol phosphate + 2-oxo-5-guanidinopentanoate
-
33% of the activity with L-glutamate
-
-
r
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate
L-histidinol phosphate + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamine
L-histidinol phosphate + 4-carbamoyl-2-oxobutanoate
-
4% of the activity with L-glutamate
-
-
r
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-histidine
L-histidinol phosphate + 3-(1H-imidazol-4-yl)-2-oxopropanoate
-
30% of the activity with L-glutamate
-
-
r
3-indole-2-oxopropanoate + L-glutamate
L-tryptophan + 2-oxoglutarate
-
-
-
?
4-methyl-2-oxopentanoate + L-alanine
L-leucine + pyruvate
-
-
-
?
4-methyl-2-oxopentanoate + L-asparagine
L-leucine + 2-oxosuccinamic acid
-
-
-
?
4-methyl-2-oxopentanoate + L-glutamate
L-leucine + 2-oxoglutarate
-
-
-
?
beta-chloro-L-alanine
pyruvate + NH3 + Cl-
-
-
-
?
L-glutarate + 2-oxobutanoate
2-oxoglutarate + 2-aminobutanoate
-
-
-
?
L-histidine + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropanoate + L-glutamate
-
-
-
-
?
L-histidinol phosphate + 2-oxo-5-guanidinopentanoate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-arginine
-
-
-
-
r
L-histidinol phosphate + 2-oxoadipate
3-(imidazol-4-yl)-2-oxopropyl phosphate + 2-aminoadipate
-
70% of the activity with 2-oxoglutarate
-
-
r
L-histidinol phosphate + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate
L-histidinol phosphate + 4-hydroxyphenylpyruvate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-tyrosine
-
-
-
-
?
L-histidinol phosphate + oxaloacetate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-aspartate
-
-
-
-
?
L-histidinol phosphate + phenylpyruvate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-phenylalanine
-
-
-
-
?
L-histidinol phosphate + pyruvate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-Ala
-
-
-
-
?
L-leucine + 2-oxoglutarate
4-methyl-2-oxopentanoate + L-glutamate
-
-
-
-
?
phenylpyruvate + L-glutamate
L-phenylalanine + 2-oxoglutarate
-
-
-
?
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate
L-histidinol phosphate + 2-oxoglutarate
histidine pathway
-
-
?
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate
L-histidinol phosphate + 2-oxoglutarate
-
eighth step in histidine biosynthesis
-
-
?
L-histidinol phosphate + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-Glu
-
-
-
-
?
L-histidinol phosphate + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-Glu
-
-
-
?
L-histidinol phosphate + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-Glu
-
i.e. imidazoleacetol phosphate + L-Glu
?
L-histidinol phosphate + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-Glu
-
-
-
?
L-histidinol phosphate + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-Glu
-
-
-
?
L-histidinol phosphate + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-Glu
-
-
i.e. imidazoleacetol phosphate + L-Glu
r
L-histidinol phosphate + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-Glu
-
-
-
-
?
L-histidinol phosphate + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-Glu
-
-
-
-
?
L-histidinol phosphate + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate
-
-
-
?
L-histidinol phosphate + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate
-
-
-
?
L-histidinol phosphate + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate
-
-
-
?
L-histidinol phosphate + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate
-
-
-
r
L-histidinol phosphate + 2-oxoglutarate
3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate
catalytic reaction pathway, histidine biosynthesis
-
-
r
L-phenylalanine + 2-oxoglutarate
phenylpyruvate + L-glutamate
-
-
-
?
L-phenylalanine + 2-oxoglutarate
phenylpyruvate + L-glutamate
-
-
-
?
L-phenylalanine + 2-oxoglutarate
phenylpyruvate + L-glutamate
low activity with
-
-
r
L-tryptophan + 2-oxoglutarate
3-indole-2-oxopropanoate + L-glutamate
-
-
-
-
?
L-tryptophan + 2-oxoglutarate
3-indole-2-oxopropanoate + L-glutamate
-
-
-
r
L-tyrosine + 2-oxoglutarate
3-(4-hydroxyphenyl)-2-oxopropanoate + glutamate
-
-
-
?
L-tyrosine + 2-oxoglutarate
3-(4-hydroxyphenyl)-2-oxopropanoate + glutamate
-
-
-
?
L-tyrosine + 2-oxoglutarate
3-(4-hydroxyphenyl)-2-oxopropanoate + glutamate
-
-
-
-
?
L-tyrosine + 2-oxoglutarate
3-(4-hydroxyphenyl)-2-oxopropanoate + L-glutamate
-
-
-
-
?
L-tyrosine + 2-oxoglutarate
3-(4-hydroxyphenyl)-2-oxopropanoate + L-glutamate
-
-
-
r
additional information
?
-
-
complete knockout of AtHPA1 is lethal for embryo
-
-
?
additional information
?
-
no substrate: 3-methyl-2-oxopentanoate, 3-methyl-2-oxobutanoate
-
-
?
additional information
?
-
-
no substrate: 3-methyl-2-oxopentanoate, 3-methyl-2-oxobutanoate
-
-
?
additional information
?
-
enzyme might also catalyze the transamination reaction with other substrates generating aromatic amino acids in vivo
-
-
?
additional information
?
-
-
enzyme might also catalyze the transamination reaction with other substrates generating aromatic amino acids in vivo
-
-
?
