2.6.1.9: histidinol-phosphate transaminase

This is an abbreviated version!
For detailed information about histidinol-phosphate transaminase, go to the full flat file.

Reaction

Synonyms

aminotransferase, histidinol phosphate, AtHPA1, glutamic-imidazoleacetol phosphate transaminase, HisC, HisC2, histidine:imidazoleacetol phosphate transaminase, histidinol phosphate aminotransferase, histidinol-phosphate aminotransferase, HspAT, IAP transaminase, imidazoleacetol phosphate transaminase, imidazolylacetolphosphate aminotransferase, imidazolylacetolphosphate transaminase, L-histidinol phosphate aminotransferase, Rv1600

ECTree

     2 Transferases

         2.6 Transferring nitrogenous groups

             2.6.1 Transaminases

                2.6.1.9 histidinol-phosphate transaminase

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Results	in table
1	Activating Compound
45158	AA Sequence
1	CAS Registry Number
8	Cloned(Commentary)
13	Cofactor
8	Crystallization (Commentary)
7	Inhibitors
3	kcat/KM [mM/s]
31	KM Value [mM]
1	Localization
10	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
29	Organism
11	Pathway
51	PDB ID
6	pH Optimum
1	pH Range
2	pH Stability
10	Protein Variants
11	Purification (Commentary)
5	Reaction
1	Reaction Type
23	Reference
1	Renatured (Commentary)
1	Source Tissue
19	Specific Activity [micromol/min/mg]
5	Storage Stability
54	Substrates and Products (Substrate)
8	Subunits
23	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
5	Temperature Stability [°C]
22	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.6.1.9 - histidinol-phosphate transaminase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate

L-histidinol phosphate + 2-oxoglutarate

2 entries

L-histidinol phosphate + 2-oxoglutarate

3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate

3 entries

additional information

?

-

3 entries

3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate

L-histidinol phosphate + 2-oxoglutarate

Escherichia coli

P06986

histidine pathway

637152

-

-

?

3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate

L-histidinol phosphate + 2-oxoglutarate

Salmonella enterica subsp. enterica serovar Typhimurium

-

eighth step in histidine biosynthesis

637143

-

-

?

L-histidinol phosphate + 2-oxoglutarate

3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate

Mycobacterium tuberculosis

P9WML7

-

758813

-

-

?

L-histidinol phosphate + 2-oxoglutarate

3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate

Mycobacterium tuberculosis H37Rv

P9WML7

-

758813

-

-

?

L-histidinol phosphate + 2-oxoglutarate

3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate

Thermotoga maritima

Q9X0D0

catalytic reaction pathway, histidine biosynthesis

659343

-

-

r

additional information

?

-

Arabidopsis thaliana

-

complete knockout of AtHPA1 is lethal for embryo

676602

-

-

?

additional information

?

-

Thermotoga maritima

Q9X0D0

enzyme might also catalyze the transamination reaction with other substrates generating aromatic amino acids in vivo

659343

-

-

?

additional information

?

-

Thermotoga maritima

-

enzyme might also catalyze the transamination reaction with other substrates generating aromatic amino acids in vivo

659343

-

-

?