2.6.1.9: histidinol-phosphate transaminase

This is an abbreviated version!
For detailed information about histidinol-phosphate transaminase, go to the full flat file.

Reaction

Synonyms

aminotransferase, histidinol phosphate, AtHPA1, glutamic-imidazoleacetol phosphate transaminase, HisC, HisC2, histidine:imidazoleacetol phosphate transaminase, histidinol phosphate aminotransferase, histidinol-phosphate aminotransferase, HspAT, IAP transaminase, imidazoleacetol phosphate transaminase, imidazolylacetolphosphate aminotransferase, imidazolylacetolphosphate transaminase, L-histidinol phosphate aminotransferase, Rv1600

ECTree

     2 Transferases

         2.6 Transferring nitrogenous groups

             2.6.1 Transaminases

                2.6.1.9 histidinol-phosphate transaminase

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Results	in table
1	Activating Compound
45158	AA Sequence
1	CAS Registry Number
8	Cloned(Commentary)
13	Cofactor
8	Crystallization (Commentary)
7	Inhibitors
3	kcat/KM [mM/s]
31	KM Value [mM]
1	Localization
10	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
29	Organism
11	Pathway
51	PDB ID
6	pH Optimum
1	pH Range
2	pH Stability
10	Protein Variants
11	Purification (Commentary)
5	Reaction
1	Reaction Type
23	Reference
1	Renatured (Commentary)
1	Source Tissue
19	Specific Activity [micromol/min/mg]
5	Storage Stability
54	Substrates and Products (Substrate)
8	Subunits
23	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
5	Temperature Stability [°C]
22	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 2.6.1.9 - histidinol-phosphate transaminase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

2-(N-morpholino)ethanesulfonic acid

Mycobacterium tuberculosis

P9WML7

specific inhibitor

739670

Co2+

Neurospora sp.

-

0.004 M, 80% inhibition

637142

Cu2+

Neurospora sp.

-

0.004 M, 80% inhibition

637142

hydroxylamine

Neurospora sp.

-

0.004 M, 80% inhibition

637142

iodoacetate

Neurospora sp.

-

0.004 M, 95% inhibition

637142

L-glutamate

Bacillus subtilis

-

competitive to tyrosine

636659

Semicarbazide

Neurospora sp.

-

0.004 M, 80% inhibition

637142