2.6.1.84: arginine-pyruvate transaminase
This is an abbreviated version!
For detailed information about arginine-pyruvate transaminase, go to the full flat file.
Reaction
Synonyms
arginine/lysine:pyruvate transaminase, arginine:pyruvate transaminase, aruF mutant, AruH, ATASE, L-arginine inducible arginine:pyruvate transaminase, L-arginine:pyruvate transaminase
ECTree
2.6.1.84 arginine-pyruvate transaminaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 2.6.1.84 - arginine-pyruvate transaminase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
L-glutamine + pyruvate
2-oxoglutaramate + L-alanine
-
broad substrate specificity, preference in decreasing order: L-arginine, L-lysine, L-methionine, L-leucine, L-ornithine, L-glutamine
-
-
?
L-lysine + pyruvate
DELTA1-piperideine-2-carboxylate + L-alanine
-
-
product identification by mass spectrometry
-
?
L-lysine + pyruvate
DELTA1-piperidine-2-carboxylate + L-alanine
-
broad substrate specificity, preference in decreasing order: L-arginine, L-lysine, L-methionine, L-leucine, L-ornithine, L-glutamine
mass spectrometry analysis, implies that AruH may have broader physiological functions in amino acid catabolism
-
?
L-methionine + pyruvate
4-methylthio-2-oxo-butanoate + L-alanine
-
-
-
-
?
L-methionine + pyruvate
4-methylthio-2-oxobutanoate + L-alanine
-
broad substrate specificity, preference in decreasing order: L-arginine, L-lysine, L-methionine, L-leucine, L-ornithine, L-glutamine
-
-
?
L-ornithine + pyruvate
5-amino-2-oxopentanoate + L-alanine
-
broad substrate specificity, preference in decreasing order: L-arginine, L-lysine, L-methionine, L-leucine, L-ornithine, L-glutamine
-
-
?
L-arginine + pyruvate
5-guanidino-2-oxopentanoate + L-alanine
-
-
-
?
L-arginine + pyruvate
5-guanidino-2-oxopentanoate + L-alanine
-
-
product identification by mass spectrometry
-
?
L-arginine + pyruvate
5-guanidino-2-oxopentanoate + L-alanine
-
AruH catalyzes the first step of the arginine transaminase pathway, representing one of the multiple pathways for L-arginine catabolism
-
-
?
L-arginine + pyruvate
5-guanidino-2-oxopentanoate + L-alanine
-
broad substrate specificity, preference in decreasing order: L-arginine, L-lysine, L-methionine, L-leucine, L-ornithine, L-glutamine
detected by HPLC and mass spectrometry
-
?
L-arginine + pyruvate
5-guanidino-2-oxopentanoate + L-alanine
-
AruH catalyzes the first step in the arginine transaminase pathway, converting the substrates L-arginine and pyruvate into 2-ketoarginine and L-alanine, AruH may have a broader physiological function in amino acid catabolism
-
-
?
L-arginine + pyruvate
5-guanidino-2-oxopentanoate + L-alanine
-
-
-
-
?
L-leucine + pyruvate
4-methyl-2-oxopentanoate + L-alanine
-
broad substrate specificity, preference in decreasing order: L-arginine, L-lysine, L-methionine, L-leucine, L-ornithine, L-glutamine
-
-
?
additional information
?
-
-
arginine utilization proceeds via multiple catabolic pathways in the organism, the enzyme is involved in the arginine transaminase pathway, regulation of arginine-responsive induction of the arginine transaminase pathway, arginine metabolism, overview
-
-
?
additional information
?
-
arginine utilization proceeds via multiple catabolic pathways in the organism, the enzyme is involved in the arginine transaminase pathway, regulation of arginine-responsive induction of the arginine transaminase pathway, arginine metabolism, overview
-
-
?
additional information
?
-
AruH is also an L-ATase, overview
-
-
?
additional information
?
-
-
broad substrate specificity in an descending order of preference: Arg, Lys, Met, Leu, Orn, Gln
-
-
?
additional information
?
-
-
knockout of aruH and aruI, which encode an arginine:pyruvate transaminase and a 2-ketoarginine decarboxylase in an operon, also abolishes the ability of the aruF mutant to grow on L-arginine
-
-
?
additional information
?
-
knockout of aruH and aruI, which encode an arginine:pyruvate transaminase and a 2-ketoarginine decarboxylase in an operon, also abolishes the ability of the aruF mutant to grow on L-arginine
-
-
?
additional information
?
-
-
arginine utilization proceeds via multiple catabolic pathways in the organism, the enzyme is involved in the arginine transaminase pathway, regulation of arginine-responsive induction of the arginine transaminase pathway, arginine metabolism, overview
-
-
?
additional information
?
-
-
AruH is also an L-ATase, overview
-
-
?
