2.6.1.77: taurine-pyruvate aminotransferase
This is an abbreviated version!
For detailed information about taurine-pyruvate aminotransferase, go to the full flat file.
Word Map on EC 2.6.1.77
-
2.6.1.77
-
sulfoacetaldehyde
-
2-aminoethanesulfonate
-
sulfur
-
sulfonate
-
bilophila
-
wadsworthia
-
transamination
-
sulfite
-
cysteate
-
sulfoacetate
-
paracoccus
-
desulfonation
-
deamination
-
rhodobacter
-
isethionate
-
acetaldehyde
-
organosulfonate
-
medicine
- 2.6.1.77
- sulfoacetaldehyde
-
2-aminoethanesulfonate
- sulfur
- sulfonate
-
bilophila
- wadsworthia
-
transamination
- sulfite
- cysteate
- sulfoacetate
-
paracoccus
-
desulfonation
-
deamination
-
rhodobacter
- isethionate
- acetaldehyde
-
organosulfonate
- medicine
Reaction
Synonyms
aminotransferase, taurine-pyruvate, HPA, hypotaurine-inducible hypotaurine:pyruvate aminotransferase, Pden_4273, taurine transaminase, taurine:pyruvate aminotransferase, tPA
ECTree
2.6.1.77 taurine-pyruvate aminotransferaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 2.6.1.77 - taurine-pyruvate aminotransferase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
taurine + 2-oxobutyrate
2-sulfoacetaldehyde + 2-aminobutyrate
-
-
?
taurine + glycolaldehyde
2-sulfoacetaldehyde + ?
-
-
-
?
taurine + glyoxylate
2-sulfoacetaldehyde + glycine
-
-
-
?
taurine + hexanal
2-sulfoacetaldehyde + hexyl-1-amine
-
-
-
?
taurine + methanal
2-sulfoacetaldehyde + methylamine
-
-
-
?
taurine + pentanal
2-sulfoacetaldehyde + pentylamine
-
-
-
?
taurine + propanal
2-sulfoacetaldehyde + propyl-1-amine
-
-
-
?
(S)-1-methylbenzylamine + pyruvate
acetophenone + L-alanine
no substrate: (R)-enantiomer
-
-
?
(S)-1-methylbenzylamine + pyruvate
acetophenone + L-alanine
no substrate: (R)-enantiomer
-
-
?
1,4-diaminobutane + pyruvate
? + L-alanine
-
3.1% of activity with taurine
-
-
?
1,4-diaminobutane + pyruvate
? + L-alanine
-
3.1% of activity with taurine
-
-
?
1,6-diaminohexane + pyruvate
? + L-alanine
-
2.6% of activity with taurine
-
-
?
1,6-diaminohexane + pyruvate
? + L-alanine
-
2.6% of activity with taurine
-
-
?
1,7-diaminoheptane + pyruvate
? + L-alanine
-
2.1% of activity with taurine
-
-
?
1-amylamine + pyruvate
pentanaldehyde + L-alanine
-
low activity
-
-
?
1-amylamine + pyruvate
pentanaldehyde + L-alanine
-
8.1% of activity with taurine
-
-
?
1-butylamine + pyruvate
4-aminobutyraldehyde + L-alanine
-
low activity
-
-
?
1-butylamine + pyruvate
4-aminobutyraldehyde + L-alanine
-
12% of activity with taurine
-
-
?
beta-alanine + pyruvate
3-oxopropanoate + L-alanine
-
best substrate
-
-
?
beta-alanine + pyruvate
3-oxopropanoate + L-alanine
-
best substrate
-
-
?
hypotaurine + pyruvate
2-aminoethanesulfinic acid + L-alanine
-
product 2-aminoethanesulfinic acid desulfinates spontaneously to acetaldehyde and sulfite
-
?
hypotaurine + pyruvate
2-aminoethanesulfinic acid + L-alanine
-
product 2-aminoethanesulfinic acid desulfinates spontaneously to acetaldehyde and sulfite
-
?
hypotaurine + pyruvate
?
i.e. 2-aminoethanesulfinate
-
-
?
spermidine + pyruvate
? + L-alanine
-
4.7% of activity with taurine
-
-
?
spermine + pyruvate
? + L-alanine
-
4.2% of activity with taurine
-
-
?
taurine + 2-oxobutanoate
2-sulfoacetaldehyde + 2-aminobutanoate
about 50% of the activity with taurine
product 2-sulfoacetaldehyde desulfinates spontaneously to acetaldehyde and sulfite
-
?
taurine + 2-oxobutanoate
2-sulfoacetaldehyde + 2-aminobutanoate
about 50% of the activity with taurine
product 2-sulfoacetaldehyde desulfinates spontaneously to acetaldehyde and sulfite
-
?
taurine + 2-oxoglutarate
2-sulfoacetaldehyde + L-glutamate
-
less active compared to pyruvate
-
-
?
taurine + 2-oxoglutarate
2-sulfoacetaldehyde + L-glutamate
-
56% of activity with pyruvate
-
-
?
taurine + butanal
2-sulfoacetaldehyde + butyl-1-amine
-
-
-
?
taurine + butanal
2-sulfoacetaldehyde + butyl-1-amine
-
-
-
?
taurine + ethanal
2-sulfoacetaldehyde + ethylamine
-
-
-
?
taurine + ethanal
2-sulfoacetaldehyde + ethylamine
-
-
-
?
taurine + pyruvate
2-sulfoacetaldehyde + L-alanine
best substrates
-
?
taurine + pyruvate
2-sulfoacetaldehyde + L-alanine
i.e. 2-aminoethanesulfonate
-
r
taurine + pyruvate
2-sulfoacetaldehyde + L-alanine
i.e. 2-aminoethanesulfonate
-
r
taurine + pyruvate
2-sulfoacetaldehyde + L-alanine
-
-
-
?
taurine + pyruvate
2-sulfoacetaldehyde + L-alanine
-
specific for taurine
-
?
taurine + pyruvate
2-sulfoacetaldehyde + L-alanine
-
i.e. 2-aminoethanesulfonate
-
?
taurine + pyruvate
2-sulfoacetaldehyde + L-alanine
-
specific for taurine
-
?
taurine + pyruvate
2-sulfoacetaldehyde + L-alanine
-
i.e. 2-aminoethanesulfonate
-
?
taurine + pyruvate
2-sulfoacetaldehyde + L-alanine
-
-
-
?
taurine + pyruvate
2-sulfoacetaldehyde + L-alanine
-
-
-
?
taurine + pyruvate
2-sulfoacetaldehyde + L-alanine
-
-
-
?
taurine + pyruvate
2-sulfoacetaldehyde + L-alanine
involved in taurine catabolism
-
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
one of several mechanisms for desulfonation
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
initial step in anaerobic taurine degradation
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
initial step in anaerobic taurine degradation
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
one of several mechanisms for desulfonation
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
essential for growth on taurine
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
initial step in anaerobic taurine degradation
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
one of several mechanisms for desulfonation
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
essential for growth on taurine
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
initial step in anaerobic taurine degradation
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
best substrate
-
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
enzyme is involved in desulfonation in the cells, the pathway produces bisulfite and acetyl phosphate, in vivo independently of pyruvate
-
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
best substrate
-
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
enzyme is involved in desulfonation in the cells, the pathway produces bisulfite and acetyl phosphate, in vivo independently of pyruvate
-
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
one of several mechanisms for desulfonation
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
initial step in anaerobic taurine degradation
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
one of several mechanisms for desulfonation
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
initial step in anaerobic taurine degradation
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
initial step in anaerobic taurine degradation
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
i.e. 2-aminoethanesulfonate
-
-
r
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
enzyme is involved in the desulfonation pathway dissimilating taurine
-
-
r
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
i.e. 2-aminoethanesulfonate
-
-
r
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
enzyme is involved in the desulfonation pathway dissimilating taurine, overview, homeostatic mechanism
-
-
r
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
i.e. 2-aminoethanesulfonate
-
-
r
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
enzyme is involved in the desulfonation pathway dissimilating taurine, overview, homeostatic mechanism
-
-
r
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
best substrate
-
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
enzyme is involved in desulfonation in the cells, the pathway produces bisulfite and acetyl phosphate, in vivo independently of pyruvate
-
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
best substrate
-
-
?
taurine + pyruvate
L-alanine + 2-sulfoacetaldehyde
-
enzyme is involved in desulfonation in the cells, the pathway produces bisulfite and acetyl phosphate, in vivo independently of pyruvate
-
-
?
taurine + pyruvate
sulfoacetaldehyde + L-alanine
-
inducible enzyme
-
-
?
additional information
?
-
no activity with 2-oxoglutarate and phenylpyruvate as amino group acceptor
-
-
?
additional information
?
-
-
no activity with 2-oxoglutarate and phenylpyruvate as amino group acceptor
-
-
?
additional information
?
-
cysteate, glutamate and 2-aminoethanephosphonate are poor amino group donor substrates
-
-
?
additional information
?
-
-
cysteate, glutamate and 2-aminoethanephosphonate are poor amino group donor substrates
-
-
?
additional information
?
-
no activity with 2-oxoglutarate and phenylpyruvate as amino group acceptor
-
-
?
additional information
?
-
-
no activity with 2-oxoglutarate and phenylpyruvate as amino group acceptor
-
-
?
additional information
?
-
cysteate, glutamate and 2-aminoethanephosphonate are poor amino group donor substrates
-
-
?
additional information
?
-
-
cysteate, glutamate and 2-aminoethanephosphonate are poor amino group donor substrates
-
-
?
additional information
?
-
-
cells grow on taurine as sole electron donor, sulfur and nitrogen source, and partial carbon source, in presence of CO2 during photoheterotrophic growth
-
-
?
additional information
?
-
-
cells grow on taurine as sole electron donor, sulfur and nitrogen source, and partial carbon source, in presence of CO2 during photoheterotrophic growth
-
-
?
additional information
?
-
the enzyme displays broad donor and acceptor ranges for unnatural substrates, with relatively good activity toward ketoses. Enzyme shows a unique mechanism of sulfonate/alpha-carboxylate recognition contributed by Arg163 and Gln160
-
-
?
additional information
?
-
the enzyme displays broad donor and acceptor ranges for unnatural substrates, with relatively good activity toward ketoses. Enzyme shows a unique mechanism of sulfonate/alpha-carboxylate recognition contributed by Arg163 and Gln160
-
-
?
additional information
?
-
-
cells grow on taurine as sole electron donor, sulfur and nitrogen source during photoautotrophic growth
-
-
?
additional information
?
-
-
cells grow on taurine as sole electron donor, sulfur and nitrogen source during photoautotrophic growth
-
-
?
