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2.6.1.73: methionine-glyoxylate transaminase

This is an abbreviated version!
For detailed information about methionine-glyoxylate transaminase, go to the full flat file.

Reaction

L-methionine
+
glyoxylate
=
4-(methylsulfanyl)-2-oxobutanoate
 +
glycine

Synonyms

aminotransferase, methionine-glyoxylate, methionine-glyoxylate aminotransferase, MGAT

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.73 methionine-glyoxylate transaminase

Substrates Products

Substrates Products on EC 2.6.1.73 - methionine-glyoxylate transaminase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
L-glutamine + 4-methylsulfanyl-2-oxobutanoate
2-oxoglutarate + L-methionine
show the reaction diagram
L-glutamine + glyoxylate
2-oxoglutarate + glycine
show the reaction diagram
L-histidine + glyoxylate
3-(1H-imidazol-4-yl)-2-oxopropanoate + glycine
show the reaction diagram
-
16% of activity compared to L-methionine
-
-
?
L-homoserine + glyoxylate
4-hydroxy-2-oxobutanoate + glycine
show the reaction diagram
-
56% of activity compared to L-methionine
-
-
?
L-methionine + 2-oxoglutarate
4-methylsulfanyl-2-oxobutanoate + L-glutamate
show the reaction diagram
-
19% of activity compared to glyoxylate
-
-
?
L-methionine + 4-methylsulfanyl-2-oxobutanoate
4-methylsulfanyl-2-oxobutanoate + L-methionine
show the reaction diagram
L-methionine + glyoxylate
4-methylsulfanyl-2-oxobutanoate + glycine
show the reaction diagram
L-methionine + oxaloacetate
4-methylsulfanyl-2-oxobutanoate + L-aspartate
show the reaction diagram
L-methionine + pyruvate
4-methylsulfanyl-2-oxobutanoate + L-alanine
show the reaction diagram
-
35% of activity compared to glyoxylate
-
-
?
L-methionine sulfone + glyoxylate
4-methylsulfonyl-2-oxobutanoate + glycine
show the reaction diagram
-
29% of activity compared to L-methionine
-
-
?
L-methionine sulfoxide + glyoxylate
4-methylsulfinyl-2-oxobutanoate + glycine
show the reaction diagram
-
54% of activity compared to L-methionine
-
-
?
L-methionine sulfoximine + glyoxylate
(S-methylsulfonimidoyl)-2-oxobutanoate + glycine
show the reaction diagram
-
35% of activity compared to L-methionine
-
-
?
S-methyl-L-cysteine + glyoxylate
3-methylsulfanyl-2-oxopropanoate + glycine
show the reaction diagram
-
49% of activity compared to L-methionine
-
-
?
additional information
?
-