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2.6.1.7: kynurenine-oxoglutarate transaminase

This is an abbreviated version!
For detailed information about kynurenine-oxoglutarate transaminase, go to the full flat file.

Word Map on EC 2.6.1.7

Reaction

L-kynurenine
+
2-oxoglutarate
=
4-(2-aminophenyl)-2,4-dioxobutanoate
 +
L-glutamate

Synonyms

AadAT, aminoadipate aminotransferase, aminotransferase, kynurenine, aspartate aminotransferase, Bna3, CCBL2, cysteine conjugate beta-lyase 1, cysteine conjugate beta-lyase 2, glutamic-oxaloacetic transaminase 2, glutamine transaminase K, KAT, KAT I, KAT II, KAT III, KAT IV, KAT-1, KAT-I, KAT-II, KAT2, KAT3, KAT3/GTL/CCBL2, KYAT3, kynurenine 2-oxoglutarate transaminase, kynurenine aminotransferase, kynurenine aminotransferase 2, kynurenine aminotransferase 3, kynurenine aminotransferase I, kynurenine aminotransferase II, kynurenine aminotransferase III, kynurenine aminotransferase IV, kynurenine aminotransferase-1, kynurenine aminotransferase-I, kynurenine aminotransferase-IV, kynurenine aminotransferases I, kynurenine aminotransferases II, kynurenine pyruvate aminotransferase, kynurenine transaminase (cyclizing), kynurenine-2-oxoglutarate aminotransferase, kynurenine/alpha-aminoadipate aminotransferase, L-kynurenine aminotransferase, mitochondrial aspartate aminotransferase, More, PhKAT, phKAT-II, type II kynurenine aminotransferase

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.7 kynurenine-oxoglutarate transaminase

Cloned

Cloned on EC 2.6.1.7 - kynurenine-oxoglutarate transaminase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
chitin-binding domain fusion proteinfusionexpressed in Escherichia coli
expressed as a glutathione S-transferase fusion protein in soluble form Escherichia coli DH5alpha cells
expressed in Escherichia coli Rosetta 2 cells
expressed in Sf9 insect cells
expression in Escherichia coli
expression in Sf9 cell
expression of full length enzyme and truncated version lacking the mitochondrial leader sequence in Sf9 insect cells
Q95VY4
expression of KAT I in Cos-1 cells
-
His-tagged protein expressed in Escherichia coli BL21-CodonPlus (DE3)
-
His-tagged protein expressed in Sf21 cells, hydrophobic interaction chromatography, gel filtration
-
maltose-binding protein fusion protein expressed in Escherichia coli BL21(DE3)
recombinant His-tagged enzyme expression in Escherichia coli, enzyme expression analysis by realtime RT-PCR
-
tagged protein (consisting of an intein and a chitin binding domain) expressed in Escherichia coli
transient expression in HEK-293 cells