2.6.1.66: valine-pyruvate transaminase
This is an abbreviated version!
For detailed information about valine-pyruvate transaminase, go to the full flat file.
Word Map on EC 2.6.1.66
-
2.6.1.66
-
alanine-valine
-
branched-chain
-
isoleucine
-
pyridoxine
-
l-alanine
-
transamination
-
typhimurium
- 2.6.1.66
-
alanine-valine
-
branched-chain
- isoleucine
- pyridoxine
- l-alanine
-
transamination
- typhimurium
Reaction
Synonyms
alanine-valine transaminase, aminotransferase, alanine-oxoisovalerate, aminotransferase, valine-pyruvate, AvtA, transaminase C
ECTree
2.6.1.66 valine-pyruvate transaminaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 2.6.1.66 - valine-pyruvate transaminase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
3-methyl-2-oxobutanoate + L-glutamate
L-valine + 2-oxoglutarate
-
-
-
-
?
3-methyl-2-oxobutanoate + L-glutamate
L-valine + 2-oxoglutarate
-
the transamination of ketoisovalerate (KIV) to valine is carried out mainly by the transaminase B enzyme, with the transaminase C enzyme playing a minor role
-
-
?
L-alanine + 3-methyl-2-oxobutanoate
L-valine + pyruvate
-
mutations in the gene encoding this enzyme are silent unless they are combined with mutations involved in isoleucine-valine biosynthesis
-
r
L-alanine + 3-methyl-2-oxobutanoate
L-valine + pyruvate
-
this enzyme deficiency results in conditional isoleucine auxotrophy in the presence of alanine
-
-
?
L-alanine + 3-methyl-2-oxobutanoate
L-valine + pyruvate
-
-
-
r
L-alanine + 3-methyl-2-oxobutanoate
L-valine + pyruvate
-
mutations in the gene encoding this enzyme are silent unless they are combined with mutations involved in isoleucine-valine biosynthesis
-
r
L-alanine + 3-methyl-2-oxobutanoate
L-valine + pyruvate
-
probably involved in alanine biosynthesis, transaminase C is found at reduced levels upon starvation for any one of several amino acids
-
r
