2.6.1.62: adenosylmethionine-8-amino-7-oxononanoate transaminase

This is an abbreviated version!
For detailed information about adenosylmethionine-8-amino-7-oxononanoate transaminase, go to the full flat file.

Word Map on EC 2.6.1.62

2.6.1.62

biotin

tuberculosis

dapas

analysis

quinonoid

dethiobiotin

antepenultimate

pyridoxal

auxotrophic

transamination

5'-phosphate-dependent

half-reaction

bicistronic

s-adenosylmethionine

plp-dependent

biotinylated

pimeloyl-coa

alpha-amino

biotechnology

pharmacology

Reaction

S-adenosyl-4-(methylsulfanyl)-2-oxobutanoate

Synonyms

7,8-diaminononanoate transaminase, 7,8-diaminopelargonate synthase, 7,8-diaminopelargonic acid aminotransferase, 7,8-diaminopelargonic acid synthase, 7,8-diaminopelargonic acid transaminase, 7,8-diaminoperlargonic acid aminotransferase, 7-keto-8-aminopelargonic acid aminotransferase, 7-keto-8-aminopelargonic acid-7,8-diaminopelargonic acid aminotransferase, Bio3-Bio1, bioA, DAPA amino transferase, DAPA aminotransferase, DAPA AT, DAPA synthase, DAPA transaminase, diaminopelargonate synthase, diaminopelargonic acid transaminase, diaminoperlargonic acid aminotransferase, More, NCgl2515, Pcryo_0361, S-adenosyl-L-methionine:8-amino-7-oxononanoate aminotransferase, synthase, diaminopelargonate

ECTree

2 Transferases

2.6 Transferring nitrogenous groups

2.6.1 Transaminases

2.6.1.62 adenosylmethionine-8-amino-7-oxononanoate transaminase

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Results	in table
22070	AA Sequence
10	Application
1	CAS Registry Number
12	Cloned(Commentary)
42	Cofactor
10	Crystallization (Commentary)
27	General Information
1	IC50 Value
81	Inhibitors
6	kcat/KM [mM/s]
23	Ki Value [mM]
58	KM Value [mM]
2	Localization
8	Molecular Weight [Da]
37	Natural Substrates/ Products (Substrates)
104	Organism
5	Pathway
113	PDB ID
10	pH Optimum
2	pH Stability
21	Protein Variants
9	Purification (Commentary)
9	Reaction
1	Reaction Type
65	Reference
10	Specific Activity [micromol/min/mg]
1	Storage Stability
138	Substrates and Products (Substrate)
6	Subunits
82	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
1	Temperature Range [°C]
5	Temperature Stability [°C]
34	Turnover Number [1/s]

Cloned

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Cloned on EC 2.6.1.62 - adenosylmethionine-8-amino-7-oxononanoate transaminase

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3 entries

cloning from strain JM101, overexpression in strain BL21(DE3)

Escherichia coli

663002

expression in Escherichia coli as truncated protein, with an N-terminal 22-residue deletion

Arabidopsis thaliana

B0F481

723412

expression in strain PY79

Bacillus subtilis

661370

gene NCgl2515, recombinant expression of His6-tagged enzyme in Escherichia coli strain BL21(DE3)

Corynebacterium glutamicum

P46395

760076

gene Pcryo-0361, recombinant expression of N-terminally His-tagged enzyme in Escherichia coli strain BL21Star

Psychrobacter cryohalolentis

Q1QDV8

758685

overexpression as mostly insoluble, N-terminally His6-tagged enzyme in Escherichia coli

Mycobacterium tuberculosis

661047

overexpression of wild-type and mutant enzymes

Escherichia coli

P12995

661088

overproduced in Escherichia coli

Mycobacterium tuberculosis

P9WQ81

673564

wild-type and R391A mutant

Escherichia coli

637095