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2.6.1.58: phenylalanine(histidine) transaminase

This is an abbreviated version!
For detailed information about phenylalanine(histidine) transaminase, go to the full flat file.

Word Map on EC 2.6.1.58

Reaction

L-phenylalanine
+
pyruvate
=
phenylpyruvate
+
L-alanine

Synonyms

aminotransferase, phenylalanine (histidine), histidine:pyruvate aminotransferase, phenylalanine (histidine) aminotransferase, phenylalanine(histidine):pyruvate aminotransferase

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.58 phenylalanine(histidine) transaminase

Substrates Products

Substrates Products on EC 2.6.1.58 - phenylalanine(histidine) transaminase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
L-glutamine + phenylpyruvate
5-amino-2,5-dioxopentanoic acid + L-phenylalanine
show the reaction diagram
-
-
-
-
?
L-histidine + pyruvate
3-(1H-imidazol-4-yl)-2-oxopropanoate + L-alanine
show the reaction diagram
-
about 50% of activity compared to L-phenylalanine
-
-
?
L-methionine + phenylpyruvate
4-methylsulfanyl-2-oxobutanoate + L-phenylalanine
show the reaction diagram
-
-
-
-
?
L-phenylalanine + pyruvate
phenylpyruvate + L-alanine
show the reaction diagram
L-serine + phenylpyruvate
3-hydroxy-2-oxopropanoate + L-phenylalanine
show the reaction diagram
-
-
-
-
?
L-tyrosine + pyruvate
3-(4-hydroxyphenyl)-2-oxopropanoate + L-alanine
show the reaction diagram
-
about 27% of activity compared to L-phenylalanine
-
-
?
additional information
?
-
-
oxaloacetate and hydroxypyruvate may replace pyruvate as amino acceptor at lower rates, little or no activity with 2-oxoglutarate
-
-
?