2.6.1.58: phenylalanine(histidine) transaminase
This is an abbreviated version!
For detailed information about phenylalanine(histidine) transaminase, go to the full flat file.
Reaction
Synonyms
aminotransferase, phenylalanine (histidine), histidine:pyruvate aminotransferase, phenylalanine (histidine) aminotransferase, phenylalanine(histidine):pyruvate aminotransferase
ECTree
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Substrates Products
Substrates Products on EC 2.6.1.58 - phenylalanine(histidine) transaminase
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REACTION DIAGRAM
L-glutamine + phenylpyruvate
5-amino-2,5-dioxopentanoic acid + L-phenylalanine
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-
-
-
?
L-histidine + pyruvate
3-(1H-imidazol-4-yl)-2-oxopropanoate + L-alanine
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about 50% of activity compared to L-phenylalanine
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-
?
L-methionine + phenylpyruvate
4-methylsulfanyl-2-oxobutanoate + L-phenylalanine
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-
-
-
?
L-tyrosine + pyruvate
3-(4-hydroxyphenyl)-2-oxopropanoate + L-alanine
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about 27% of activity compared to L-phenylalanine
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-
?
additional information
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oxaloacetate and hydroxypyruvate may replace pyruvate as amino acceptor at lower rates, little or no activity with 2-oxoglutarate
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