2.6.1.56: 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase

This is an abbreviated version!
For detailed information about 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase, go to the full flat file.

Reaction

Synonyms

guanidinoaminodideoxy-scyllo-inositol-pyruvate aminotransferase, L-alanine-N-amidino-3-(or 5-)keto-scyllo-inosamine transaminase

ECTree

     2 Transferases

         2.6 Transferring nitrogenous groups

             2.6.1 Transaminases

                2.6.1.56 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase

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Results	in table
1	CAS Registry Number
1	Cofactor
1	General Stability
4	Natural Substrates/ Products (Substrates)
5	Organism
3	Pathway
1	Reaction
1	Reaction Type
5	Reference
13	Substrates and Products (Substrate)
2	Synonyms
1	Systematic Name
1	Temperature Stability [°C]

Substrates Products

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Substrates Products on EC 2.6.1.56 - 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

L-alanine + 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol

pyruvate + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol

6 entries

L-glutamate + 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol

5-amino-2,5-dioxopentanoic acid + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol

Streptomyces bikiniensis

-

-

640163, 640164

-

-

r

L-glutamine + 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol

alpha-ketoglutaramate + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol

2 entries

additional information

?

-

Streptomyces bikiniensis

-

D-amino acids are no substrates, also catalyzes transamination between 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol and 1D-1-guanidino-1-deoxy-3-keto-scyllo inositol

640164

-

-

?

L-alanine + 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol

pyruvate + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol

Streptomyces bikiniensis

-

-

640163

-

640163

r

L-alanine + 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol

pyruvate + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol

Streptomyces bikiniensis

-

-

640164

-

-

r

L-alanine + 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol

pyruvate + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol

Streptomyces bikiniensis

-

streptomycin biosynthesis

640164

-

-

?

L-alanine + 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol

pyruvate + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol

Streptomyces bikiniensis

-

streptomycin biosynthesis

640163

-

640163

r

L-alanine + 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol

pyruvate + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol

Streptomyces griseus

-

-

640164

-

-

?, r

L-alanine + 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol

pyruvate + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol

Streptomyces ornatus

-

-

640164

-

-

?, r

L-glutamine + 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol

alpha-ketoglutaramate + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol

Streptomyces bikiniensis

-

-

640163

-

-

ir

L-glutamine + 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol

alpha-ketoglutaramate + 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol

Streptomyces bikiniensis

-

reaction should be relatively irreversible because of cyclization or enzymic deamidation of the alpha-ketoglutaramate formed

640164

-

-

ir