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2.6.1.5: tyrosine transaminase

This is an abbreviated version!
For detailed information about tyrosine transaminase, go to the full flat file.

Word Map on EC 2.6.1.5

Reaction

L-tyrosine
+
2-oxoglutarate
=
4-hydroxyphenylpyruvate
 +
L-glutamate

Synonyms

aminotransferase, tyrosine, At5g36160, At5g53970, beta-phenylalanine aminotransferase, glutamic phenylpyruvic aminotransferase, glutamic-hydroxyphenylpyruvic transaminase, L-phenylalanine 2-oxoglutarate aminotransferase, L-tyrosine aminotransferase, L-tyrosine-2-oxoglutarate aminotransferase, L-tyrosine: 2 oxoglutarate aminotransferase, L-tyrosine: 2-oxoglutarate aminotransferase, More, mTAT, phenylalanine aminotransferase, phenylalanine transaminase, phenylalanine-alpha-ketoglutarate transaminase, phenylpyruvate transaminase, phenylpyruvic acid transaminase, PPY-AT, Sar2028, TAT, TAT1, TAT2, TAT3, TATase, TATc, Tyr aminotransferase, TyrAT, tyrosine aminotransferase, tyrosine-2-ketoglutarate aminotransferase, tyrosine-2-oxoglutarate aminotransferase, tyrosine-alpha-ketoglutarate aminotransferase, tyrosine-alpha-ketoglutarate transaminase, VpAT

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.5 tyrosine transaminase

Expression

Expression on EC 2.6.1.5 - tyrosine transaminase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
cardiac-specific miR-133a overexpression prevents upregulation of the enzyme expression in the heart after streptozotocin is administered
enzyme mRNA is expressed abundantly in the glandular and luminal epithelia of the oviducts in response to endogenous and exogenous estrogens
gene expression of isoform TAT2 is upregulated under drought stress
gene expression of isoform TAT3 is upregulated under drought stress
in a combined culture of hepatocytes and non-parenchymal liver cells, reproducing intercellular interactions in vitro, cortisol and non-parenchymal cells exhibit an additive effect on TAT activity
-
in starved trout, TyrAT activity in liver and white muscle is about 64 and 267%, respectively, higher than control. After 9 days of refeeding, the control values recover, although, at 6 h of refeeding, hepatic TyrAT activity is higher than that for starvation
-
miR-133a mimic treatment improves the contractility of the diabetic rat's heart concomitant with downregulation of the enzyme
the enzyme activity is induced by the intraperitoneal injection of hydrocortisone in a dose of 50 mg/kg or dexamethasone phosphate in a dose of 5 mg/kg of body weight. Ortho-aminoazotoluene decreases enzyme induction by hydrocortisone by more than 40%
-
when rats are maintained on a vitamin B12-deficient diet, the activity of tyrosine aminotransferase in the liver is significantly reduced compared with those in the B12-sufficient control rats
-