2.6.1.45: serine-glyoxylate transaminase
This is an abbreviated version!
For detailed information about serine-glyoxylate transaminase, go to the full flat file.
Word Map on EC 2.6.1.45
-
2.6.1.45
-
hyperoxaluria
-
peroxisomal
-
oxalate
-
pyridoxal
-
hydroxypyruvate
-
liver-specific
-
mistargeting
-
pyridoxine
-
photorespiration
-
photorespiratory
-
oxalosis
-
2.6.1.44
-
glutamate:glyoxylate
-
hyphomicrobium
-
urolithiasis
-
nephrocalcinosis
-
methylovorum
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peroxisome-to-mitochondrion
-
intraperoxisomal
-
liver-kidney
-
anlage
-
plp-dependent
-
agriculture
- 2.6.1.45
- hyperoxaluria
- peroxisomal
- oxalate
- pyridoxal
- hydroxypyruvate
-
liver-specific
-
mistargeting
- pyridoxine
-
photorespiration
-
photorespiratory
- oxalosis
-
2.6.1.44
-
glutamate:glyoxylate
- hyphomicrobium
- urolithiasis
- nephrocalcinosis
- methylovorum
-
peroxisome-to-mitochondrion
-
intraperoxisomal
-
liver-kidney
-
anlage
-
plp-dependent
- agriculture
Reaction
Synonyms
AGT1, alanine:glyoxylate aminotransferase, aminotransferase, serine-glyoxylate, FpSGAT, L-serine glyoxylate aminotransferase, More, Os08g0502700, serine-alpha-ketoglutarate aminotransferase, serine-glyoxylate aminotranferase, serine-glyoxylate aminotransferase, serine:glyoxylate aminotransferase, serine:glyoxylate transaminase, Sga, Sga20Z, SgaBath, SGAT, SGT, SKAT
ECTree
2.6.1.45 serine-glyoxylate transaminaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 2.6.1.45 - serine-glyoxylate transaminase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
L-alanine + 2-oxomalonate
pyruvate + 2-aminomalonate
-
-
-
?
L-asparagine + hydroxypyruvate
2-oxosuccinamate + L-serine
-
20% of L-serine transamination activity
-
?
L-serine + 2-oxosuccinamate
3-hydroxypyruvate + L-asparagine
-
poor substrate
-
?
L-serine + 3-hydroxypyruvate
3-hydroxypyruvate + L-serine
-
-
-
?
L-serine + hydroxypyruvate
3-hydroxypyruvate + L-serine
-
poor substrate
-
?
L-alanine + glyoxylate
pyruvate + glycine
55% of the activity with L-serine and glyoxylate
-
-
?
L-alanine + glyoxylate
pyruvate + glycine
reaction of alanine-glyoxylate aminotransferase (AGAT), EC 2.6.1.44
-
-
?
L-alanine + glyoxylate
pyruvate + glycine
reaction of alanine-glyoxylate aminotransferase (AGAT), EC 2.6.1.44
-
-
?
L-alanine + glyoxylate
pyruvate + glycine
reaction of alanine-glyoxylate aminotransferase (AGAT), EC 2.6.1.44
-
-
?
L-alanine + glyoxylate
pyruvate + glycine
reaction of alanine-glyoxylate aminotransferase (AGAT), EC 2.6.1.44
-
-
?
L-alanine + glyoxylate
pyruvate + glycine
reaction of alanine-glyoxylate aminotransferase (AGAT), EC 2.6.1.44
-
-
?
L-alanine + glyoxylate
pyruvate + glycine
reaction of alanine-glyoxylate aminotransferase (AGAT), EC 2.6.1.44
-
-
?
L-alanine + glyoxylate
pyruvate + glycine
Methylotuvimicrobium alcaliphilum DSM 19304
reaction of alanine-glyoxylate aminotransferase (AGAT), EC 2.6.1.44
-
-
?
L-alanine + glyoxylate
pyruvate + glycine
Methylotuvimicrobium alcaliphilum NCIMB 14124
reaction of alanine-glyoxylate aminotransferase (AGAT), EC 2.6.1.44
-
-
?
L-alanine + glyoxylate
pyruvate + glycine
Methylotuvimicrobium alcaliphilum VKM B-2133
reaction of alanine-glyoxylate aminotransferase (AGAT), EC 2.6.1.44
-
-
?
L-alanine + glyoxylate
pyruvate + glycine
-
20% of L-serine transamination activity
-
?
L-asparagine + glyoxylate
2-oxosuccinamate + glycine
-
transamination at 38% the rate of L-serine
-
r
L-asparagine + glyoxylate
2-oxosuccinamate + glycine
-
20% of L-serine transamination actiivty
-
r
L-serine + 2-oxoglutarate
3-hydroxypyruvate + L-glutamate
-
-
-
?
L-serine + 2-oxoglutarate
3-hydroxypyruvate + L-glutamate
-
-
-
?
L-serine + 2-oxoglutarate
3-hydroxypyruvate + L-glutamate
-
-
-
?
L-serine + 2-oxoglutarate
3-hydroxypyruvate + L-glutamate
-
-
-
?
L-serine + 2-oxoglutarate
3-hydroxypyruvate + L-glutamate
-
-
-
?
L-serine + 2-oxoglutarate
3-hydroxypyruvate + L-glutamate
-
-
-
?
L-serine + 2-oxoglutarate
3-hydroxypyruvate + L-glutamate
Methylotuvimicrobium alcaliphilum DSM 19304
-
-
-
?
L-serine + 2-oxoglutarate
3-hydroxypyruvate + L-glutamate
Methylotuvimicrobium alcaliphilum NCIMB 14124
-
-
-
?
L-serine + 2-oxoglutarate
3-hydroxypyruvate + L-glutamate
Methylotuvimicrobium alcaliphilum VKM B-2133
-
-
-
?
L-serine + 2-oxomalonate
3-hydroxypyruvate + 2-aminomalonate
-
-
-
?
L-serine + 2-oxomalonate
3-hydroxypyruvate + 2-aminomalonate
-
-
-
?
L-serine + 2-oxomalonate
3-hydroxypyruvate + 2-aminomalonate
-
-
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
reaction in photorespiratory glycolate pathway
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
reduced activity in vivo results in the accumulation of serine and to a smaller extend, of glycine, indicating that the flux through the photorespiratory pathway is restricted
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
-
-
ir
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
highly specific
-
ir
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
no activity with Phe, Arg, Val, Trp, Thr, Met
-
ir
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
nearly irreversible, trace amounts of L-serine
-
ir
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
no activity with D-serine
-
ir
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
no or trace activity with oxaloacetate, 2-oxoglutarate
-
ir
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
no activity with Ala, Glu, Gln, His, oxamate, 2-oxo-n-butanoate, 3-methyl-2-oxo-butanoate, 2-methyl-DL-serine, L-serine-O-sulfate, DL-serine hydroxamate, O-phospho-L-serine
-
ir
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
plays essential role in methanol assimilation through serine pathway
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
part of the C-1 assimilation pathway
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
preferred substrates
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
preferred substrates
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
preferred substrates
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
preferred substrates
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
Methylorubrum extorquens ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1
-
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
preferred substrates
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
preferred substrates
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
preferred substrates
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
Methylotuvimicrobium alcaliphilum DSM 19304
preferred substrates
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
Methylotuvimicrobium alcaliphilum NCIMB 14124
preferred substrates
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
Methylotuvimicrobium alcaliphilum VKM B-2133
preferred substrates
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
reverse reaction at 4-11% the rate of forward reaction
-
r
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
preferred substrates
-
r
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
preferred substrates
-
r
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
involved in glycine metabolism
-
-
?
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
no activity with Phe, Arg, Val, Trp, Thr, Met
-
r
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
reverse reaction at 4-11% the rate of forward reaction
-
r
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
preferred substrates
-
r
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
no or trace activity with oxaloacetate, 2-oxoglutarate
-
r
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
no activity with Tyr, Ile, Pro, Cys, Leu, Asp
-
r
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
equilibrium towards glycine production
-
r
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
reverse reaction at 4-11% the rate of forward reaction
-
r
L-serine + glyoxylate
3-hydroxypyruvate + glycine
-
physiologically irreversible
-
-
?
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
reaction of serine-pyruvate aminotransferase (SPAT), EC 2.6.1.51
-
-
?
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
reaction of serine-pyruvate aminotransferase (SPAT), EC 2.6.1.51
-
-
?
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
reaction of serine-pyruvate aminotransferase (SPAT), EC 2.6.1.51
-
-
?
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
reaction of serine-pyruvate aminotransferase (SPAT), EC 2.6.1.51
-
-
?
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
-
reaction of serine-pyruvate aminotransferase (SPAT), EC 2.6.1.51
-
-
?
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
reaction of serine-pyruvate aminotransferase (SPAT), EC 2.6.1.51
-
-
?
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
reaction of serine-pyruvate aminotransferase (SPAT), EC 2.6.1.51
-
-
?
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
Methylotuvimicrobium alcaliphilum DSM 19304
reaction of serine-pyruvate aminotransferase (SPAT), EC 2.6.1.51
-
-
?
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
Methylotuvimicrobium alcaliphilum NCIMB 14124
reaction of serine-pyruvate aminotransferase (SPAT), EC 2.6.1.51
-
-
?
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
Methylotuvimicrobium alcaliphilum VKM B-2133
reaction of serine-pyruvate aminotransferase (SPAT), EC 2.6.1.51
-
-
?
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
-
-
-
?
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
-
6% of glyoxylate transamination activity
-
r
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
-
8% of glyoxylate transamination activity
-
r
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
-
equilibrium towards alanine production
-
r
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
-
8% of glyoxylate transamination activity
-
?
L-serine + pyruvate
3-hydroxypyruvate + L-alanine
-
poor substrate, 10% of glyoxylate transamination activity
-
?
